Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.53 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.44 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.44 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | CA12 | O43570 | 8/20 | 0.36 |
| ▸ | CA1 | P00915 | 8/20 | 0.36 |
| ▸ | CA2 | P00918 | 8/20 | 0.36 |
| ▸ | CA9 | Q16790 | 8/20 | 0.36 |
| ▸ | CA7 | P43166 | 6/20 | 0.36 |
| ▸ | CA14 | Q9ULX7 | 6/20 | 0.36 |
| ▸ | LMNA | P02545 | 3/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | USP2 | O75604 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | PDCD1 | Q15116 | 1/20 | 0.32 |
| ▸ | CD274 | Q9NZQ7 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL297916 | 0.86 | TSHR (0.59) | TSHRADRA1APDE4DHCAR2GAA | |
| SCHEMBL10991690 | 0.83 | TSHR (0.43) | TSHRADRA1APDE4DHCAR2GAA | |
| SCHEMBL20262459 | 0.83 | TSHR (0.43) | TSHRADRA1APDE4DHCAR2GAA | |
| SCHEMBL20262471 | 0.81 | TSHR (0.48) | TSHRADRA1APDE4DHCAR2GAA | |
| SCHEMBL10866275 | 0.81 | TSHR (0.42) | TSHRADRA1APDE4DHCAR2GAA | |
| SCHEMBL10866267 | 0.81 | TSHR (0.42) | TSHRADRA1APDE4DHCAR2GAA | |
| SCHEMBL16048299 | 0.80 | TSHR (0.53) | TSHRADRA1APDE4DHCAR2GAA | |
| SCHEMBL20565358 | 0.80 | TSHR (0.53) | TSHRADRA1APDE4DHCAR2GAA | |
| SCHEMBL20262409 | 0.79 | TSHR (0.40) | TSHRADRA1APDE4DHCAR2GAA | |
| SCHEMBL890983 | 0.78 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4132611-A | Addition of organic electrophiles to carbon acids via catalysis by electrogenerated bases | MONSANTO COMPANY (US) | 1979-01-02 | — | — | US | disclosed |
| US-4072583-A | Electrolytic carboxylation of carbon acids via electrogenerated bases | MONSANTO COMPANY (US) | 1978-02-07 | — | — | US | disclosed |