⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29119777 | 0.97 | TSHR (0.48) | — | |
| SCHEMBL297916 | 0.83 | TSHR (0.59) | — | |
| SCHEMBL1003135 | 0.82 | — | — | |
| SCHEMBL28267250 | 0.82 | TSHR (0.46) | — | |
| SCHEMBL27926059 | 0.80 | TSHR (0.56) | — | |
| SCHEMBL5316505 | 0.79 | — | — | |
| SCHEMBL11703818 | 0.78 | TSHR (0.42) | — | |
| SCHEMBL11510451 | 0.78 | TSHR (0.53) | — | |
| SCHEMBL20565358 | 0.78 | TSHR (0.53) | — | |
| SCHEMBL16048299 | 0.78 | TSHR (0.53) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 55 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119977783-A | Synthesis method of oxaloacetic acid | 上海高准医药有限公司 | 2025-05-13 | — | — | CN | claimed |
| CN-116768795-A | Synthesis method of cyenopyrafen intermediate | 湖南速博生物技术有限公司 | 2023-09-19 | — | — | CN | claimed |
| EP-0026982-A1 | Coating compositions containing mono- or diester coalescing agents and a substrate coated therewith | ROHM AND HAAS COMPANY (US) | 1981-04-15 | — | — | EP | claimed |
| CN-119977783-A | Synthesis method of oxaloacetic acid | 上海高准医药有限公司 | 2025-05-13 | — | — | CN | disclosed |
| CN-115485276-B | Deuterated AKT kinase inhibitors | 南京正大天晴制药有限公司 | 2024-05-31 | — | — | CN | disclosed |
| CN-117964620-A | AKT inhibitors | 南京正大天晴制药有限公司 | 2024-05-03 | — | — | CN | disclosed |
| CN-113272304-B | AKT inhibitors | 南京正大天晴制药有限公司 | 2024-03-29 | — | — | CN | disclosed |
| CN-115843298-B | Salts and crystal forms of dihydropyrido [2,3-d ] pyrimidinone derivative | 南京正大天晴制药有限公司 | 2024-03-29 | — | — | CN | disclosed |
| CN-115836069-B | Salts of dihydropyrido [2,3-d ] pyrimidinone derivatives, preparation method and application thereof | 南京正大天晴制药有限公司 | 2024-02-06 | — | — | CN | disclosed |
| US-20230321108-A1 | UNIT DOSAGE COMPOSITION OF AKT INHIBITOR | NANJING CHIA TAI TIANQING PHARMACEUTICAL CO., LTD. (CN) | 2023-10-12 | — | — | US | disclosed |
| US-20230271958-A1 | SALT AND CRYSTAL FORM OF DIHYDROPYRIDO[2,3-d]PYRIMIDINE DERIVATE | NANJING CHIA TAI TIANQING PHARMACEUTICAL CO., LTD. (CN) | 2023-08-31 | — | — | US | disclosed |
| EP-0983268-A1 | AMIDINE DERIVATIVES AS INHIBITORS OF NITRIC OXIDE SYNTHASE | Astra Aktiebolag (SE) | 2000-03-08 | — | — | EP | disclosed |
| US-6018072-A | SUBJECTING AN ALKYLARYL OXALATE TO A DISPROPORTIONATION REACTION IN THE PRESENCE OF A DISPROPORTIONATION CATALYST TO PRODUCE A DIARYL OXALATE WHILE REMOVING A DIALKYL OXALATE BY-PRODUCT | UBE INDUSTRIES, LTD. (JP) | 2000-01-25 | — | — | US | disclosed |
| WO-1998050382-A1 | AMIDINE DERIVATIVES AS INHIBITORS OF NITRIC OXIDE SYNTHASE | ASTRA AKTIEBOLAG (SE) | 1998-11-12 | — | — | WO | disclosed |
| US-5811573-A | Process for producing a diaryl carnonate | UBE INDUSTRIES, LTD. (JP) | 1998-09-22 | — | — | US | disclosed |
| US-5731453-A | Process for producing a diaryl carbonate | UBE INDUSTRIES, LTD. (JP) | 1998-03-24 | — | — | US | disclosed |
| EP-0814074-A1 | PROCESS FOR PREPARING DIARYL ESTERS OF OXALIC ACID | UBE INDUSTRIES, LTD. (JP) | 1997-12-29 | — | — | EP | disclosed |
| EP-0795539-A1 | Process for producing a diaryl carbonate | UBE INDUSTRIES LIMITED (JP) | 1997-09-17 | — | — | EP | disclosed |
| US-4863949-A | CARDIOVASCULAR DISORDER TREATMENT | BOEHRINGER MANNHEIM GMBH (DE) | 1989-09-05 | — | — | US | disclosed |
| US-4435048-A | LARGE AREA OPTICAL DISPLAY | ASAHI GLASS COMPANY LTD. (JP) | 1984-03-06 | — | — | US | disclosed |