Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GABRA1 | P14867 | 1/20 | 0.52 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.52 |
| ▸ | TSHR | P16473 | 2/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.43 |
| ▸ | ALOX15 | P16050 | 4/20 | 0.43 |
| ▸ | POLB | P06746 | 3/20 | 0.43 |
| ▸ | CA2 | P00918 | 3/20 | 0.43 |
| ▸ | LMNA | P02545 | 3/20 | 0.43 |
| ▸ | HPGD | P15428 | 3/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.43 |
| ▸ | NPC1 | O15118 | 2/20 | 0.43 |
| ▸ | EGFR | P00533 | 2/20 | 0.43 |
| ▸ | FYN | P06241 | 2/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | MMP9 | P14780 | 2/20 | 0.43 |
| ▸ | CA4 | P22748 | 2/20 | 0.43 |
| ▸ | RECQL | P46063 | 2/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL133407 | 0.84 | GABRA1 (0.62) | GABRA1GABRB2TSHRALDH1A1ALOX15 | |
| SCHEMBL30194816 | 0.84 | GABRA1 (0.62) | GABRA1GABRB2TSHRALDH1A1ALOX15 | |
| SCHEMBL11611313 | 0.79 | GABRA1 (0.56) | GABRA1GABRB2TSHRALDH1A1ALOX15 | |
| SCHEMBL7623488 | 0.77 | GABRA1 (0.54) | GABRA1GABRB2TSHRALDH1A1ALOX15 | |
| SCHEMBL11125456 | 0.75 | GABRA1 (0.52) | GABRA1GABRB2TSHRALDH1A1ALOX15 | |
| SCHEMBL11510892 | 0.75 | GABRA1 (0.52) | GABRA1GABRB2TSHRALDH1A1ALOX15 | |
| SCHEMBL671174 | 0.75 | GABRA1 (0.65) | GABRA1GABRB2TSHRALDH1A1ALOX15 | |
| SCHEMBL990718 | 0.75 | GABRA1 (0.65) | GABRA1GABRB2TSHRALDH1A1ALOX15 | |
| SCHEMBL30195663 | 0.73 | GABRA1 (0.62) | GABRA1GABRB2TSHRALDH1A1ALOX15 | |
| SCHEMBL29407501 | 0.73 | GABRA1 (0.62) | GABRA1GABRB2TSHRALDH1A1ALOX15 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4144027-A | SHRINKPROOFING KERATIN-CONTAINING FABRICS BY REACTION WITH A POLYETHER POLYOL AND A DIISOCYANATE | MILLIKEN RESEARCH CORPORATION (US) | 1979-03-13 | — | — | US | disclosed |