Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 2/20 | 0.55 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.52 |
| ▸ | HDAC2 | Q92769 | 6/20 | 0.51 |
| ▸ | PTK2 | Q05397 | 4/20 | 0.51 |
| ▸ | HDAC1 | Q13547 | 4/20 | 0.50 |
| ▸ | HDAC3 | O15379 | 3/20 | 0.50 |
| ▸ | HDAC8 | Q9BY41 | 3/20 | 0.50 |
| ▸ | HDAC6 | Q9UBN7 | 3/20 | 0.50 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.48 |
| ▸ | TSHR | P16473 | 2/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.46 |
| ▸ | HTT | P42858 | 2/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.46 |
| ▸ | MEN1 | O00255 | 2/20 | 0.46 |
| ▸ | NPC1 | O15118 | 2/20 | 0.46 |
| ▸ | RAB9A | P51151 | 2/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22019056 | 0.85 | GAA (0.60) | GAARXFP1CTDSP1TDP1L3MBTL1 | |
| SCHEMBL1545115 | 0.78 | GAA (0.54) | GAARXFP1CTDSP1TDP1L3MBTL1 | |
| SCHEMBL11510724 | 0.75 | GAA (0.40) | GAARXFP1TSHRCYP3A4KMT2A | |
| SCHEMBL11510033 | 0.74 | HDAC2 (0.67) | GAAHDAC2PTK2HDAC1HDAC3 | |
| SCHEMBL11511237 | 0.74 | GAA (0.43) | GAAHDAC2PTK2HDAC1TSHR | |
| SCHEMBL15983686 | 0.74 | GAA (0.59) | GAARXFP1CTDSP1TDP1L3MBTL1 | |
| SCHEMBL1544760 | 0.73 | GAA (0.45) | GAARXFP1CTDSP1TDP1L3MBTL1 | |
| SCHEMBL11510747 | 0.72 | ALDH1A1 (0.47) | GAATDP1TSHRKMT2AHTT | |
| SCHEMBL1545084 | 0.72 | GAA (0.46) | GAARXFP1CTDSP1TDP1L3MBTL1 | |
| SCHEMBL15986408 | 0.71 | RXFP1 (0.79) | GAARXFP1TDP1L3MBTL1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4178253-A | 1,2,4-TRIAZOLE COMPOUNDS | CIBA-GEIGY CORPORATION (US) | 1979-12-11 | — | — | US | disclosed |