Biphenyl

Biphenyl

SCHEMBL11511546

ClCCCl.c1ccc(-c2ccccc2)cc1

nearest known ligand 0.64

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Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 4/20 0.64
CYP1A2 P05177 1/20 0.53
TAAR1 Q96RJ0 3/20 0.46
MAPK1 P28482 2/20 0.45
CYP3A4 P08684 1/20 0.45
HSD17B10 Q99714 1/20 0.45
TDP1 Q9NUW8 1/20 0.45
NOTUM Q6P988 1/20 0.45
MMP3 P08254 1/20 0.45
BCL2L1 Q07817 1/20 0.45
NPC1 O15118 2/20 0.43
HTT P42858 2/20 0.43
RAB9A P51151 2/20 0.43
MITF O75030 1/20 0.43
SMN1; SMN2 Q16637 1/20 0.43
ATM Q13315 1/20 0.41
SLC22A2 O15244 1/20 0.41
SLC22A1 O15245 1/20 0.41
SLC22A3 O75751 1/20 0.41
SLC6A4 P31645 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Tannin Pyrogallol SCHEMBL27755771 0.97 ALDH1A1 (0.60) ALDH1A1CYP1A2TAAR1MAPK1CYP3A4
Biphenyl SCHEMBL151980 0.89 ALDH1A1 (0.69) ALDH1A1CYP1A2TAAR1MAPK1CYP3A4
Tannin Pyrogallol SCHEMBL28290079 0.86 ALDH1A1 (0.64) ALDH1A1CYP1A2TAAR1MAPK1CYP3A4
Biphenyl SCHEMBL28774143 0.86 ALDH1A1 (0.64) ALDH1A1CYP1A2TAAR1MAPK1CYP3A4
Biphenyl SCHEMBL27772106 0.84 ALDH1A1 (0.53) ALDH1A1CYP1A2TAAR1MAPK1CYP3A4
Biphenyl SCHEMBL27598181 0.83 ALDH1A1 (0.60) ALDH1A1CYP1A2TAAR1MAPK1CYP3A4
Biphenyl SCHEMBL9388941 0.81 ALDH1A1 (0.82) ALDH1A1CYP1A2TAAR1MAPK1CYP3A4
Biphenyl SCHEMBL1358618 0.80 ALDH1A1 (1.00) ALDH1A1CYP1A2TAAR1MAPK1CYP3A4
Biphenyl SCHEMBL2548048 0.80 ALDH1A1 (1.00) ALDH1A1CYP1A2TAAR1MAPK1CYP3A4
Biphenyl SCHEMBL164 0.80 ALDH1A1 (1.00) ALDH1A1CYP1A2TAAR1MAPK1CYP3A4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-101429137-A Process for producing p-phenyl cyanophenyl CINIC CHEMICALS SHANGHAI CO LT (CN) 2009-05-13 CN disclosed
US-4156099-A TRIFLUOROMETHANESULFONIC ACID CATALYST GENERAL ELECTRIC COMPANY (US) 1979-05-22 US disclosed
US-4107442-A Process for preparing dihydroxydiphenyl chloroethylenes GENERAL ELECTRIC COMPANY (US) 1978-08-15 US disclosed