Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TAAR1 | Q96RJ0 | 4/20 | 0.46 |
| ▸ | PNMT | P11086 | 2/20 | 0.44 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.42 |
| ▸ | MAOA | P21397 | 1/20 | 0.42 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.42 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.42 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.42 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.42 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.42 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.42 |
| ▸ | HTR2A | P28223 | 2/20 | 0.41 |
| ▸ | HTR2C | P28335 | 2/20 | 0.41 |
| ▸ | HTR2B | P41595 | 2/20 | 0.41 |
| ▸ | SLC7A5 | Q01650 | 2/20 | 0.41 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.40 |
| ▸ | PPARG | P37231 | 1/20 | 0.36 |
| ▸ | PPARA | Q07869 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7774587 | 0.86 | TAAR1 (0.50) | TAAR1 | |
| SCHEMBL1049748 | 0.86 | EPHX1 (0.58) | TAAR1SLC6A2MAOASLC6A4SLC6A3 | |
| SCHEMBL11513417 | 0.85 | TAAR1 (0.43) | TAAR1PNMTSLC6A2MAOASLC6A4 | |
| SCHEMBL11511513 | 0.82 | TAAR1 (0.41) | TAAR1PNMTSLC6A2MAOASLC6A4 | |
| SCHEMBL11512652 | 0.79 | TAAR1 (0.53) | TAAR1PNMTSLC6A2MAOASLC6A4 | |
| SCHEMBL11511250 | 0.77 | TAAR1 (0.40) | TAAR1PNMTSLC6A2MAOASLC6A4 | |
| SCHEMBL16390151 | 0.76 | TSHR (0.42) | TAAR1MAOASLC6A4EPHX1 | |
| SCHEMBL14599873 | 0.76 | PRSS1 (0.41) | TAAR1PNMTSLC7A5EPHX1 | |
| SCHEMBL4392230 | 0.74 | TAAR1 (0.57) | TAAR1SLC6A2SLC7A5 | |
| SCHEMBL11517459 | 0.74 | TAAR1 (0.38) | TAAR1PNMTSLC6A2MAOASLC6A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4171203-A | IN COMBINATION WITH A TETRAAMINOPYRIMIDING COUPLER SURFACTANTS AND THICKENERS | HENKEL KOMMANDITGESELLSCHAFT AUF AKTIEN (DE) | 1979-10-16 | — | — | US | disclosed |