SCHEMBL4392230

SCHEMBL4392230

CCOC(N)Cc1ccc(O)cc1

nearest known ligand 0.57

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
TAAR1 Q96RJ0 3/20 0.57
SLC6A2 P23975 1/20 0.57
ESR1 P03372 5/20 0.47
ESR2 Q92731 5/20 0.47
SLC7A5 Q01650 1/20 0.47
IDO1 P14902 2/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4387614 0.85 TAAR1 (0.53) TAAR1SLC6A2ESR1ESR2SLC7A5
SCHEMBL16390151 0.82 TSHR (0.42) TAAR1
SCHEMBL5710979 0.82 TAAR1 (0.52) TAAR1SLC6A2ESR1ESR2SLC7A5
SCHEMBL4394050 0.80 TAAR1 (0.61) TAAR1SLC6A2ESR1ESR2SLC7A5
SCHEMBL1049748 0.80 EPHX1 (0.58) TAAR1SLC6A2SLC7A5
SCHEMBL1840449 0.78 TAAR1 (0.53) TAAR1SLC6A2ESR1ESR2SLC7A5
SCHEMBL13457372 0.78 TAAR1 (0.53) TAAR1SLC6A2ESR1ESR2SLC7A5
SCHEMBL4392676 0.77 TAAR1 (0.62) TAAR1SLC6A2ESR1ESR2SLC7A5
SCHEMBL9576635 0.76 ESR1 (0.55) TAAR1SLC6A2ESR1ESR2
SCHEMBL7254097 0.76 ESR1 (0.46) TAAR1SLC6A2ESR1ESR2SLC7A5

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8227390-B2 Binder resin for friction material, binder resin composition for friction material, composite material for friction material containing the same, friction material and production method thereof AKEBONO BRAKE INDUSTRY CO., LTD. (JP) 2012-07-24 US disclosed
US-20090137434-A1 BINDER RESIN FOR FRICTION MATERIAL, BINDER RESIN COMPOSITION FOR FRICTION MATERIAL, COMPOSITE MATERIAL FOR FRICTION MATERIAL CONTAINING THE SAME, FRICTION MATERIAL AND PRODUCTION METHOD THEREOF AKEBONO BRAKE INDUSTRY CO., LTD (JP) 2009-05-28 US disclosed
EP-0460128-A1 AGENT AND PROCESS FOR THE OXIDATIVE DYEING OF HAIR. WELLA AG (DE) 1991-12-11 EP disclosed