Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTAFR | P25105 | 19/20 | 0.59 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.57 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.57 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.51 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11510242 | 0.86 | OPRK1 (0.46) | PTAFROPRK1PDE4DCYP3A4ALOX15 | |
| SCHEMBL11509934 | 0.85 | PTAFR (0.79) | PTAFROPRK1PDE4D | |
| SCHEMBL11508913 | 0.85 | OPRK1 (0.44) | PTAFROPRK1PDE4DCYP3A4ALOX15 | |
| SCHEMBL11507904 | 0.85 | PTAFR (0.69) | PTAFROPRK1PDE4DCYP3A4ALOX15 | |
| SCHEMBL10509168 | 0.85 | OPRK1 (0.61) | PTAFROPRK1PDE4DCYP3A4ALOX15 | |
| SCHEMBL11507350 | 0.84 | OPRK1 (0.45) | PTAFROPRK1PDE4DCYP3A4ALOX15 | |
| SCHEMBL11508877 | 0.82 | PTAFR (0.47) | PTAFROPRK1PDE4DCYP3A4ALOX15 | |
| SCHEMBL11508119 | 0.82 | PTAFR (0.65) | PTAFROPRK1PDE4D | |
| SCHEMBL9661363 | 0.82 | PTAFR (0.62) | PTAFROPRK1PDE4DCYP3A4ALOX15 | |
| SCHEMBL11510006 | 0.80 | PTAFR (0.62) | PTAFROPRK1PDE4D |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4155913-A | ANTICONBULSANTS, MUSCLE RELAXANTS AND SEDATIVES | HOFFMANN-LA ROCHE INC. (US) | 1979-05-22 | — | — | US | disclosed |