Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 5/20 | 0.62 |
| ▸ | MAPT | P10636 | 5/20 | 0.62 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.62 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.62 |
| ▸ | THRB | P10828 | 3/20 | 0.62 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.62 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.62 |
| ▸ | IDO1 | P14902 | 2/20 | 0.59 |
| ▸ | ALOX5 | P09917 | 2/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.47 |
| ▸ | GAA | P10253 | 3/20 | 0.44 |
| ▸ | BLM | P54132 | 2/20 | 0.44 |
| ▸ | TP53 | P04637 | 1/20 | 0.44 |
| ▸ | ATM | Q13315 | 1/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | SYK | P43405 | 2/20 | 0.43 |
| ▸ | ASPH | Q12797 | 1/20 | 0.42 |
| ▸ | RIOX2 | Q8IUF8 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11513224 | 0.85 | KDM4E (0.68) | MEN1MAPTKMT2AKDM4ETHRB | |
| SCHEMBL9750717 | 0.84 | IDO1 (0.61) | MEN1MAPTKMT2AKDM4ETHRB | |
| SCHEMBL4342011 | 0.83 | KDM4E (0.52) | MEN1MAPTKMT2AKDM4ETHRB | |
| SCHEMBL4347717 | 0.82 | MEN1 (0.69) | MEN1MAPTKMT2AKDM4ETHRB | |
| SCHEMBL6130238 | 0.82 | IDO1 (0.56) | MEN1MAPTKMT2AKDM4ETHRB | |
| SCHEMBL4348993 | 0.82 | MAPT (0.46) | MEN1MAPTKMT2AKDM4ETHRB | |
| SCHEMBL11510707 | 0.81 | IDO1 (0.49) | MEN1MAPTKMT2AKDM4ETHRB | |
| SCHEMBL268673 | 0.80 | KDM4E (0.78) | MEN1MAPTKMT2AKDM4ETHRB | |
| SCHEMBL4347345 | 0.79 | GAA (0.67) | MEN1MAPTKMT2AKDM4ETHRB | |
| SCHEMBL11026552 | 0.79 | HDAC1 (0.60) | MEN1MAPTKMT2AKDM4ETHRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4152452-A | N-BENZYLANILINE AND DERIVATIVES | WILLIAM H. RORER, INC. (US) | 1979-05-01 | — | — | US | disclosed |