Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC1 | Q13547 | 1/20 | 0.60 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.60 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.60 |
| ▸ | MEN1 | O00255 | 3/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.50 |
| ▸ | MAPT | P10636 | 2/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.50 |
| ▸ | THRB | P10828 | 1/20 | 0.50 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.49 |
| ▸ | IDO1 | P14902 | 1/20 | 0.47 |
| ▸ | CISD1 | Q9NZ45 | 1/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.44 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.44 |
| ▸ | PKM | P14618 | 1/20 | 0.42 |
| ▸ | CA12 | O43570 | 1/20 | 0.42 |
| ▸ | CA1 | P00915 | 1/20 | 0.42 |
| ▸ | CA2 | P00918 | 1/20 | 0.42 |
| ▸ | CA3 | P07451 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11510637 | 0.82 | HDAC1 (0.59) | HDAC1HDAC8HDAC6MEN1KMT2A | |
| SCHEMBL11513224 | 0.82 | KDM4E (0.68) | MEN1KMT2AMAPTKDM4EALDH1A1 | |
| SCHEMBL2316630 | 0.81 | HSD17B10 (0.59) | HDAC1HDAC8HDAC6MEN1KMT2A | |
| SCHEMBL11512059 | 0.79 | MEN1 (0.62) | MEN1KMT2AMAPTKDM4EALDH1A1 | |
| SCHEMBL2553849 | 0.76 | HDAC8 (0.72) | HDAC1HDAC8HDAC6MEN1KMT2A | |
| SCHEMBL7237335 | 0.76 | KDM4E (0.46) | HDAC1HDAC8HDAC6MEN1KMT2A | |
| SCHEMBL5511518 | 0.76 | TDP1 (0.57) | HDAC1HDAC8HDAC6MEN1KMT2A | |
| SCHEMBL5700244 | 0.75 | MRGPRX4 (0.66) | HDAC1HDAC8HDAC6MEN1KMT2A | |
| SCHEMBL20613056 | 0.74 | MEN1 (0.61) | MEN1KMT2AKDM4EALDH1A1L3MBTL1 | |
| SCHEMBL20613057 | 0.74 | P2RX7 (0.39) | HDAC1HDAC8HDAC6MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0033443-B1 | AZO DYESTUFFS, THEIR PREPARATION AND USE IN DYEING SYNTHETIC FIBRES | BAYER AG (DE) | 1985-05-08 | — | — | EP | disclosed |
| EP-0033443-A1 | Azo dyestuffs, their preparation and use in dyeing synthetic fibres | BAYER AG (DE) | 1981-08-12 | — | — | EP | disclosed |