SCHEMBL11512166

SCHEMBL11512166

CCNC(=S)Nc1ccc(C)cc1C

nearest known ligand 0.71

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 4/20 0.71
MEN1 O00255 3/20 0.71
ALOX12 P18054 7/20 0.63
LMNA P02545 6/20 0.63
ALDH1A1 P00352 4/20 0.62
MCHR1 Q99705 1/20 0.62
L3MBTL1 Q9Y468 1/20 0.62
HTT P42858 3/20 0.61
GAA P10253 4/20 0.59
SMN1; SMN2 Q16637 4/20 0.59
NPSR1 Q6W5P4 1/20 0.59
HPGD P15428 1/20 0.59
TDP1 Q9NUW8 1/20 0.59
MAPK1 P28482 1/20 0.56

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11515272 0.87 KMT2A (0.77) KMT2AMEN1ALOX12LMNAALDH1A1
SCHEMBL31388347 0.85 KMT2A (0.71) KMT2AMEN1ALOX12LMNAALDH1A1
SCHEMBL11514074 0.84 KMT2A (0.73) KMT2AMEN1ALOX12LMNAALDH1A1
SCHEMBL11513633 0.83 LMNA (0.53) KMT2AMEN1ALOX12LMNAALDH1A1
SCHEMBL6097065 0.83 SMN1; SMN2 (0.78) ALOX12LMNAALDH1A1MCHR1HTT
SCHEMBL11512780 0.83 LMNA (0.57) KMT2AMEN1ALOX12LMNAALDH1A1
SCHEMBL5454958 0.83 KMT2A (1.00) KMT2AMEN1ALOX12LMNAALDH1A1
SCHEMBL11804063 0.81 KMT2A (0.64) KMT2AMEN1ALOX12LMNAALDH1A1
SCHEMBL11814225 0.81 KMT2A (0.83) KMT2AMEN1ALOX12LMNAALDH1A1
SCHEMBL11513904 0.81 KMT2A (0.64) KMT2AMEN1ALOX12LMNAALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4173645-A INSECTICIDES, MITICIDES BAYER AKTIENGESELLSCHAFT (DE) 1979-11-06 US disclosed
US-4148799-A Process for the preparation of 2-aryliminothiazoline solutions BAYER AKTIENGESELLSCHAFT (DE) 1979-04-10 US disclosed