Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.49 |
| ▸ | SLCO2A1 | Q92959 | 2/20 | 0.49 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.49 |
| ▸ | TBXA2R | P21731 | 8/20 | 0.48 |
| ▸ | LMNA | P02545 | 4/20 | 0.48 |
| ▸ | PTGFR | P43088 | 3/20 | 0.48 |
| ▸ | PTGER4 | P35408 | 3/20 | 0.48 |
| ▸ | PTGER1 | P34995 | 2/20 | 0.48 |
| ▸ | PTGER3 | P43115 | 2/20 | 0.48 |
| ▸ | PTGDR | Q13258 | 1/20 | 0.48 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | HPGD | P15428 | 3/20 | 0.43 |
| ▸ | ABCC4 | O15439 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 2/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.43 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.43 |
| ▸ | PTGER2 | P43116 | 2/20 | 0.42 |
| ▸ | PTGIR | P43119 | 2/20 | 0.42 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11512253 | 1.00 | ALDH1A1 (0.49) | ALDH1A1SLCO2A1PTGDR2TBXA2RLMNA | |
| SCHEMBL11512251 | 1.00 | ALDH1A1 (0.49) | ALDH1A1SLCO2A1PTGDR2TBXA2RLMNA | |
| SCHEMBL11508944 | 0.84 | TBXA2R (0.47) | ALDH1A1SLCO2A1PTGDR2TBXA2RLMNA | |
| SCHEMBL11508942 | 0.84 | TBXA2R (0.47) | ALDH1A1SLCO2A1PTGDR2TBXA2RLMNA | |
| SCHEMBL11508946 | 0.84 | TBXA2R (0.47) | ALDH1A1SLCO2A1PTGDR2TBXA2RLMNA | |
| SCHEMBL11510388 | 0.81 | TBXA2R (0.56) | ALDH1A1SLCO2A1PTGDR2TBXA2RLMNA | |
| SCHEMBL11510387 | 0.81 | TBXA2R (0.56) | ALDH1A1SLCO2A1PTGDR2TBXA2RLMNA | |
| SCHEMBL11510385 | 0.81 | TBXA2R (0.56) | ALDH1A1SLCO2A1PTGDR2TBXA2RLMNA | |
| SCHEMBL11550008 | 0.79 | TBXA2R (0.56) | ALDH1A1SLCO2A1TBXA2RLMNAPTGFR | |
| SCHEMBL11509906 | 0.76 | TBXA2R (0.48) | ALDH1A1SLCO2A1PTGDR2TBXA2RLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4144251-A | PROSTAGLANDINS | AMERICAN HOME PRODUCTS CORPORATION (US) | 1979-03-13 | — | — | US | disclosed |