SCHEMBL11512340

SCHEMBL11512340

CCCCNS(C)(=O)=O.[NaH]

nearest known ligand 0.64

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
CA1 P00915 5/20 0.64
CA2 P00918 5/20 0.64
CA12 O43570 3/20 0.64
CA14 Q9ULX7 3/20 0.64
CA7 P43166 2/20 0.64
PPARA Q07869 4/20 0.48
POLB P06746 1/20 0.45
EPHX1 P07099 1/20 0.43
ALDH1A1 P00352 1/20 0.42
MEN1 O00255 1/20 0.40
HTT P42858 1/20 0.40
KMT2A Q03164 1/20 0.40
ADH1B P00325 1/20 0.39
ADH1C P00326 1/20 0.39
ADH1A P07327 1/20 0.39
ADH7 P40394 1/20 0.39
TSHR P16473 1/20 0.38
CA9 Q16790 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL487521 0.97
SCHEMBL327308 0.90 PPARA (0.60) CA1CA2CA12CA14CA7
SCHEMBL1703464 0.87 PPARA (0.64) CA1CA2CA12CA14CA7
SCHEMBL11335730 0.87 PPARA (0.64) CA1CA2CA12CA14CA7
SCHEMBL1679669 0.87 PPARA (0.64) CA1CA2CA12CA14CA7
SCHEMBL5696662 0.87 PPARA (0.64) CA1CA2CA12CA14CA7
SCHEMBL11326328 0.87 PPARA (0.64) CA1CA2CA12CA14CA7
SCHEMBL5020900 0.87 PPARA (0.64) CA1CA2CA12CA14CA7
SCHEMBL2694822 0.87 PPARA (0.64) CA1CA2CA12CA14CA7
SCHEMBL10312301 0.87 PPARA (0.64) CA1CA2CA12CA14CA7

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4161524-A INSECTICIDES, MITICIDES, NEMATOCIDES BAYER AKTIENGESELLSCHAFT (DE) 1979-07-17 US disclosed
US-4134979-A INSECTICIDES, MITICIDES, NEMATOCIDES BAYER AKTIENGESELLSCHAFT (DE) 1979-01-16 US disclosed