Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 1/20 | 0.48 |
| ▸ | TSHR | P16473 | 2/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.46 |
| ▸ | GAA | P10253 | 2/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.44 |
| ▸ | HPGD | P15428 | 2/20 | 0.44 |
| ▸ | USP2 | O75604 | 1/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.43 |
| ▸ | NQO2 | P16083 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | NLRP3 | Q96P20 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11512914 | 0.95 | GAA (0.43) | HTTTSHRSMN1; SMN2GAAALDH1A1 | |
| SCHEMBL9492570 | 0.87 | HTT (0.51) | HTTTSHRSMN1; SMN2KDM4ELMNA | |
| SCHEMBL11110801 | 0.84 | HTT (0.49) | HTTTSHRSMN1; SMN2KDM4ELMNA | |
| SCHEMBL668453 | 0.84 | TSHR (0.56) | HTTTSHRALDH1A1LMNAKMT2A | |
| SCHEMBL3936078 | 0.82 | TSHR (0.51) | HTTTSHRSMN1; SMN2GAAALDH1A1 | |
| SCHEMBL1397958 | 0.81 | HTT (0.56) | HTTTSHRSMN1; SMN2LMNAKMT2A | |
| SCHEMBL11513567 | 0.80 | HTT (0.57) | HTTTSHRLMNAKMT2ANQO2 | |
| SCHEMBL11512586 | 0.80 | KMT2A (0.54) | HTTTSHRSMN1; SMN2LMNAKMT2A | |
| SCHEMBL9206004 | 0.79 | HTT (0.59) | HTTTSHRSMN1; SMN2ALDH1A1LMNA | |
| SCHEMBL6528311 | 0.79 | TSHR (0.50) | HTTTSHRALDH1A1LMNAKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4162325-A | PHARMACEUTICAL ACTIVITY ON THE MNEMIC PROCESSES | UCB, SOCIETE ANONYME (BE) | 1979-07-24 | — | — | US | disclosed |