Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.56 |
| ▸ | GSK3A | P49840 | 1/20 | 0.46 |
| ▸ | GSK3B | P49841 | 1/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.45 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 4/20 | 0.44 |
| ▸ | ELANE | P08246 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | PIN1 | Q13526 | 1/20 | 0.41 |
| ▸ | PIN4 | Q9Y237 | 1/20 | 0.41 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.41 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.41 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6528311 | 0.95 | TSHR (0.50) | TSHRGSK3AGSK3BHTTLMNA | |
| SCHEMBL9821321 | 0.94 | TSHR (0.50) | TSHRGSK3AGSK3BHTTPIK3CD | |
| SCHEMBL6495319 | 0.93 | TSHR (0.49) | TSHRGSK3AGSK3BHTTLMNA | |
| SCHEMBL9708708 | 0.89 | GSK3A (0.49) | TSHRGSK3AGSK3BLMNAELANE | |
| SCHEMBL3936078 | 0.89 | TSHR (0.51) | TSHRHTTPIK3CDLMNAKMT2A | |
| SCHEMBL9821162 | 0.88 | TSHR (0.44) | TSHRGSK3AGSK3BLMNAELANE | |
| SCHEMBL11514599 | 0.87 | TSHR (0.46) | TSHRHTTPIK3CDLMNAALDH1A1 | |
| SCHEMBL2931487 | 0.86 | TSHR (0.59) | TSHRHTTPIK3CDLMNAKMT2A | |
| SCHEMBL14048407 | 0.84 | TSHR (0.50) | TSHRHTTPIK3CDLMNAKMT2A | |
| SCHEMBL3939476 | 0.84 | TSHR (0.46) | TSHRGSK3AGSK3BHTTLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 69 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116183763-A9 | Impurity detection method of piracetam injection | 北京星昊盈盛药业有限公司 | 2024-01-05 | — | — | CN | claimed |
| CN-116183763-A | Impurity detection method of piracetam injection | 北京星昊盈盛药业有限公司 | 2023-05-30 | — | — | CN | claimed |
| CN-115734964-A | Preparation method of levetiracetam intermediate | 浙江华海药业股份有限公司 | 2023-03-03 | — | — | CN | claimed |
| US-6716857-B2 | 1-(3-HYDROCARBYLOXYIMINO-3-(1-ALKYL-1,2,5,6-TETRAHYDROPYRID-3-YL) -ALKYLPYRROLIDIN-2-ONE DERIVATIVES; RECEPTIVITY; ANALGESICS, GLAUCOMA, PSYCHOSIS, SCHIZOPHRENIA, ANXIOLYTIC AGENTS, BIPOLAR DISORDERS; ANTIDEPRESSANTS; SLEEP DISORDERS | KOREA INSTITUTE OF SCIENCE AND TECHNOLOGY (KR) | 2004-04-06 | — | — | US | claimed |
| US-20030119880-A1 | Tetrahydropyridine derivatives acting on muscarinic acetylcholine receptors | KOREA INSTITUTE OF SCIENCE AND TECHNOLOGY (KR) | 2003-06-26 | — | — | US | claimed |
| CN-117647600-A | Impurity detection method of piracetam injection | 华中药业股份有限公司 | 2024-03-05 | — | — | CN | disclosed |
| CN-116183763-A9 | Impurity detection method of piracetam injection | 北京星昊盈盛药业有限公司 | 2024-01-05 | — | — | CN | disclosed |
| CN-117263952-A | Condensed-cyclic compound, preparation method and application thereof | 四川科伦博泰生物医药股份有限公司 | 2023-12-22 | — | — | CN | disclosed |
| CN-110278711-B | Tricyclosulfones as rory modulators | 百时美施贵宝公司 | 2023-12-15 | — | — | CN | disclosed |
| CN-111836814-B | Condensed-cyclic compound, preparation method and application thereof | 四川科伦博泰生物医药股份有限公司 | 2023-10-20 | — | — | CN | disclosed |
| CN-116903485-A | Synthesis method of Piracetam related substance E | 山东玉满坤生物科技有限公司 | 2023-10-20 | — | — | CN | disclosed |
| CN-116183763-A | Impurity detection method of piracetam injection | 北京星昊盈盛药业有限公司 | 2023-05-30 | — | — | CN | disclosed |
| EP-0089900-A1 | New N-((2-oxo-1-pyrrolidinyl)acetyl)piperazines, the methods of producing such new compounds and their salts as well as pharmaceutical preparations for therapeutic use containing these compounds or salts | PRODES S.A. (ES) | 1983-09-28 | — | — | EP | disclosed |
| US-4332728-A | Process for the preparation of bisacyl hydrazines | RUTGERSWERKE AKTIENGESELLSCHAFT (DE) | 1982-06-01 | — | — | US | disclosed |
| US-4324787-A | 2-Oxo-1-pyrrolidineacetic acid compounds and their medicinal use | TROPONWERKE GMBH & CO., KG (DE) | 1982-04-13 | — | — | US | disclosed |
| EP-0003029-B1 | NEW 2-OXO-1-PYRROLIDINE ACETIC ACID DERIVATIVES, PROCESS FOR THEIR PREPARATION, MEDICAMENTS CONTAINING THEM AND PROCESS FOR THEIR PREPARATION | Troponwerke GmbH & Co. KG (DE) | 1980-12-10 | — | — | EP | disclosed |
| EP-0003029-A2 | New 2-oxo-1-pyrrolidine acetic acid derivatives, process for their preparation, medicaments containing them and process for their preparation | Troponwerke GmbH & Co. KG (DE) | 1979-07-25 | — | — | EP | disclosed |
| US-4145347-A | TREATMENT OF SENILITY, AMNESIA AND LEARNING DISORDERS | PARKE, DAVIS & COMPANY (US) | 1979-03-20 | — | — | US | disclosed |
| US-4123548-A | (2-Oxo-pyrrolidines)-acetic hydrazides | CHEMISCHES LABORATORIUM FRITZ-WALTER LANGE GMBH & CO KG (DE) | 1978-10-31 | — | — | US | disclosed |
| US-4069336-A | PSYCHOPHARMACONS, NOOTROPIC AGENTS | CHEMISCHES LABORATORIUM FRITZ-WALTER LANGE GMBH & CO KG (DT) | 1978-01-17 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030119880-A1 | Tetrahydropyridine derivatives acting on muscarinic acetylcholine receptors | CHRM1, CHRM3, CHRM2 | TSHR 92/4885GSK3A 3117/4885GSK3B 3087/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.