Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.48 |
| ▸ | HPGD | P15428 | 2/20 | 0.48 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.41 |
| ▸ | TXNRD1 | Q16881 | 1/20 | 0.40 |
| ▸ | TXNRD3 | Q86VQ6 | 1/20 | 0.40 |
| ▸ | TXNRD2 | Q9NNW7 | 1/20 | 0.40 |
| ▸ | NOS1 | P29475 | 2/20 | 0.38 |
| ▸ | NOS2 | P35228 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 4/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.37 |
| ▸ | MGAM | O43451 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | SI | P14410 | 1/20 | 0.37 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.37 |
| ▸ | LIPG | Q9Y5X9 | 2/20 | 0.36 |
| ▸ | MAPT | P10636 | 3/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.36 |
| ▸ | POLB | P06746 | 2/20 | 0.36 |
| ▸ | RAB9A | P51151 | 2/20 | 0.36 |
| ▸ | USP2 | O75604 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15880366 | 0.81 | PDE10A (0.44) | ALDH1A1PDE10ATXNRD1TXNRD3TXNRD2 | |
| SCHEMBL2381198 | 0.78 | PSMB8 (0.56) | ALDH1A1HPGDPDE10ATXNRD1TXNRD3 | |
| SCHEMBL9037145 | 0.75 | PSMB8 (0.59) | ALDH1A1HPGDPDE10AMEN1KMT2A | |
| SCHEMBL11516404 | 0.75 | ALDH1A1 (0.51) | ALDH1A1HPGDMEN1KMT2AGAA | |
| SCHEMBL31122218 | 0.74 | PDE10A (0.49) | ALDH1A1HPGDPDE10ATXNRD1TXNRD3 | |
| SCHEMBL10426653 | 0.74 | PDE10A (0.49) | ALDH1A1HPGDPDE10ATXNRD1TXNRD3 | |
| SCHEMBL4920165 | 0.74 | ALDH1A1 (0.50) | ALDH1A1PDE10ATXNRD1TXNRD3TXNRD2 | |
| SCHEMBL15880740 | 0.73 | TDP1 (0.48) | ALDH1A1PDE10ATXNRD1TXNRD3TXNRD2 | |
| SCHEMBL1011902 | 0.73 | ALDH1A1 (0.53) | ALDH1A1PDE10ATXNRD1TXNRD3TXNRD2 | |
| SCHEMBL10666612 | 0.73 | PDE10A (0.47) | ALDH1A1HPGDPDE10ATXNRD1TXNRD3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4146712-A | PROCESS FOR THE MANUFACTURE OF COUMARIN DYES | CIBA-GEIGY CORPORATION (US) | 1979-03-27 | — | — | US | disclosed |
| US-4064136-A | FROM A NITRILE, AN ALCOHOL AND ORTHO-SUBSTITUTED AROMATIC AMINE | CIBA-GEIGY AG (CH) | 1977-12-20 | — | — | US | disclosed |