Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.56 |
| ▸ | TSHR | P16473 | 2/20 | 0.51 |
| ▸ | HTT | P42858 | 1/20 | 0.49 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.44 |
| ▸ | NQO2 | P16083 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.40 |
| ▸ | ADRA1D | P25100 | 4/20 | 0.39 |
| ▸ | ADRA1A | P35348 | 4/20 | 0.39 |
| ▸ | ADRA1B | P35368 | 4/20 | 0.39 |
| ▸ | ATAD2 | Q6PL18 | 1/20 | 0.39 |
| ▸ | CECR2 | Q9BXF3 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11512972 | 1.00 | LMNA (0.56) | LMNATSHRHTTPIK3CDSMN1; SMN2 | |
| SCHEMBL11514634 | 0.87 | LMNA (0.57) | LMNATSHRHTTPIK3CDSMN1; SMN2 | |
| SCHEMBL20666231 | 0.85 | LMNA (0.64) | LMNATSHRHTTPIK3CDSMN1; SMN2 | |
| SCHEMBL24796427 | 0.83 | LMNA (0.53) | LMNATSHRHTTPIK3CDSMN1; SMN2 | |
| SCHEMBL24796333 | 0.83 | LMNA (0.53) | LMNATSHRHTTPIK3CDSMN1; SMN2 | |
| SCHEMBL21389318 | 0.83 | LMNA (0.48) | LMNATSHRHTTPIK3CDSMN1; SMN2 | |
| SCHEMBL21389518 | 0.83 | LMNA (0.48) | LMNATSHRHTTPIK3CDSMN1; SMN2 | |
| SCHEMBL11105944 | 0.82 | LMNA (0.53) | LMNATSHRHTTPIK3CDSMN1; SMN2 | |
| SCHEMBL21389519 | 0.81 | LMNA (0.57) | LMNATSHRHTTPIK3CDKMT2A | |
| SCHEMBL24796419 | 0.81 | LMNA (0.57) | LMNATSHRHTTPIK3CDKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4162325-A | PHARMACEUTICAL ACTIVITY ON THE MNEMIC PROCESSES | UCB, SOCIETE ANONYME (BE) | 1979-07-24 | — | — | US | disclosed |