Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 5/20 | 0.36 |
| ▸ | USP2 | O75604 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | DGAT1 | O75907 | 1/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.32 |
| ▸ | HMGCR | P04035 | 1/20 | 0.32 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.32 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.32 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.32 |
| ▸ | MGAM | O43451 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | SI | P14410 | 1/20 | 0.32 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.32 |
| ▸ | TET2 | Q6N021 | 1/20 | 0.31 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.31 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.31 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.31 |
| ▸ | RECQL | P46063 | 2/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | HPGD | P15428 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10011917 | 0.79 | TSHR (0.40) | TSHRUSP2LMNADGAT1HSD17B10 | |
| SCHEMBL4128811 | 0.75 | TSHR (0.39) | TSHRLMNADGAT1HSD17B10HMGCR | |
| SCHEMBL10012726 | 0.74 | DGAT1 (0.38) | TSHRUSP2LMNADGAT1HSD17B10 | |
| SCHEMBL10012861 | 0.74 | GAA (0.47) | TSHRUSP2LMNADGAT1HSD17B10 | |
| SCHEMBL10010486 | 0.73 | TSHR (0.34) | TSHRUSP2LMNADGAT1HSD17B10 | |
| SCHEMBL10011688 | 0.73 | TSHR (0.34) | TSHRUSP2LMNADGAT1HSD17B10 | |
| SCHEMBL15412844 | 0.73 | TSHR (0.42) | TSHRUSP2LMNADGAT1HSD17B10 | |
| SCHEMBL3280983 | 0.73 | TSHR (0.42) | TSHRUSP2LMNADGAT1HSD17B10 | |
| SCHEMBL12716750 | 0.72 | TSHR (0.46) | TSHRUSP2LMNADGAT1HSD17B10 | |
| SCHEMBL10011126 | 0.72 | CA12 (0.33) | TSHRUSP2LMNADGAT1HSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4170607-A | Carboxymethyloxysuccinic anhydrides, halides and derivatives thereof | LEVER BROTHERS COMPANY (US) | 1979-10-09 | — | — | US | disclosed |
| US-4169842-A | CARBOXYMETHYLOXYSUCCINIC ANHYDRIDE AND ACID HALIDE THEREOF | LEVER BROTHERS COMPANY (US) | 1979-10-02 | — | — | US | disclosed |
| US-4169957-A | AMIDES OF CARBOXYMETHYLOXYSUCCINIC ACID | LEVER BROTHERS COMPANY (US) | 1979-10-02 | — | — | US | disclosed |
| US-4167523-A | FLAVORS, FUEL ADDITIVES, LUBRICANTS, SURFACTANTS, BUILDERS, COATINGS | LEVER BROTHERS COMPANY (US) | 1979-09-11 | — | — | US | disclosed |
| US-4167524-A | FOOD FLAVORINGS, DETERGENT BUILDERS, SURFACTANTS, LUBRICATNS, COATINGS, SIZING AGENTS, FUEL ADDITIVES | LEVER BROTHERS COMPANY (US) | 1979-09-11 | — | — | US | disclosed |
| US-4137409-A | Morpholino carboxymethyloxysuccinic anhydrides, halides and derivatives thereof | LEVER BROTHERS COMPANY (US) | 1979-01-30 | — | — | US | disclosed |
| US-4093634-A | Anhydrides of carboxymethyloxysuccinic acid | LEVER BROTHERS COMPANY (US) | 1978-06-06 | — | — | US | disclosed |
| US-4081420-A | Carboxymethyloxysuccinic acid esters as plastic plasticizers | LEVER BROTHERS COMPANY (US) | 1978-03-28 | — | — | US | disclosed |
| US-3996150-A | DETERGENT WITH SURFACTANT, BUILDER | LEVER BROTHERS COMPANY (US) | 1976-12-07 | — | — | US | disclosed |
| US-3943165-A | DETERGENT SOLVENTS, PLASTICIZERS | LEVER BROTHERS COMPANY (US) | 1976-03-09 | — | — | US | disclosed |