Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 4/20 | 0.51 |
| ▸ | MAPK1 | P28482 | 4/20 | 0.51 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.51 |
| ▸ | TSHR | P16473 | 2/20 | 0.51 |
| ▸ | MAPT | P10636 | 3/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.43 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.43 |
| ▸ | TXNRD1 | Q16881 | 1/20 | 0.43 |
| ▸ | TXNRD3 | Q86VQ6 | 1/20 | 0.43 |
| ▸ | TXNRD2 | Q9NNW7 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | PTPN5 | P54829 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | HPD | P32754 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11513950 | 0.82 | CYP3A4 (0.61) | TDP1MAPK1CYP3A4TSHRMAPT | |
| Ethalfluralin SCHEMBL55014 | 0.81 | CYP3A4 (0.64) | TDP1MAPK1CYP3A4TSHRMAPT | |
| Ethalfluralin SCHEMBL4899703 | 0.81 | CYP3A4 (0.64) | TDP1MAPK1CYP3A4TSHRMAPT | |
| SCHEMBL11643284 | 0.81 | CYP3A4 (0.52) | TDP1MAPK1CYP3A4TSHRMAPT | |
| SCHEMBL11514125 | 0.80 | TDP1 (0.70) | TDP1MAPK1CYP3A4TSHRMAPT | |
| SCHEMBL135804 | 0.79 | TDP1 (0.76) | TDP1MAPK1CYP3A4TSHRMAPT | |
| SCHEMBL9451050 | 0.79 | TDP1 (0.76) | TDP1MAPK1CYP3A4TSHRMAPT | |
| SCHEMBL9445547 | 0.73 | CYP3A4 (0.47) | TDP1MAPK1CYP3A4TSHRMAPT | |
| SCHEMBL11515702 | 0.73 | CYP3A4 (0.59) | TDP1MAPK1CYP3A4TSHRMAPT | |
| SCHEMBL8857960 | 0.72 | CYP3A4 (0.63) | TDP1MAPK1CYP3A4TSHRMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4143073-A | REACTION OF SUBSTITUTED N-ALKOXY-2,6-DINITROANILINES WITH ALKYL OR ALKENYL HALIDE IN PRESENCE OF SODIUM HYDRIDE | ELI LILLY AND COMPANY (US) | 1979-03-06 | — | — | US | disclosed |
| US-4087460-A | HERBICIDES, PLANT GROWTH REGULATORS, CHEMICAL INTERMEDIATES | ELI LILLY AND COMPANY (US) | 1978-05-02 | — | — | US | disclosed |