Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 4/20 | 0.47 |
| ▸ | MAPT | P10636 | 2/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.47 |
| ▸ | MEN1 | O00255 | 2/20 | 0.47 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | HPGD | P15428 | 2/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | CNR1 | P21554 | 1/20 | 0.43 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.43 |
| ▸ | KDM5B | Q9UGL1 | 1/20 | 0.43 |
| ▸ | FFAR1 | O14842 | 3/20 | 0.42 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.42 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.42 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.42 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11511112 | 0.87 | KMT2A (0.47) | KMT2AMAPTL3MBTL1MEN1HDAC8 | |
| SCHEMBL11511132 | 0.83 | HSD17B10 (0.47) | KMT2AMAPTL3MBTL1MEN1HDAC8 | |
| SCHEMBL11513066 | 0.79 | HDAC8 (0.44) | KMT2AMAPTL3MBTL1MEN1HDAC8 | |
| SCHEMBL18666372 | 0.78 | MEN1 (0.56) | KMT2AMAPTMEN1ALDH1A1MAPK1 | |
| SCHEMBL7349396 | 0.76 | KMT2A (0.51) | KMT2AMAPTL3MBTL1MEN1HDAC8 | |
| SCHEMBL11510347 | 0.76 | FFAR1 (0.63) | KMT2AMAPTL3MBTL1MEN1ALDH1A1 | |
| SCHEMBL11512300 | 0.75 | HDAC8 (0.44) | KMT2AMAPTL3MBTL1MEN1HDAC8 | |
| SCHEMBL11510710 | 0.75 | FFAR1 (0.57) | KMT2AMAPTMEN1FFAR1GABRG2 | |
| SCHEMBL11511508 | 0.75 | FFAR1 (0.54) | KMT2AMAPTMEN1ALDH1A1KDM4E | |
| SCHEMBL11511152 | 0.75 | FFAR1 (0.53) | KMT2AMAPTMEN1HDAC8ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4152452-A | N-BENZYLANILINE AND DERIVATIVES | WILLIAM H. RORER, INC. (US) | 1979-05-01 | — | — | US | disclosed |