Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.54 |
| ▸ | LMNA | P02545 | 1/20 | 0.54 |
| ▸ | TP53 | P04637 | 1/20 | 0.51 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.51 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.48 |
| ▸ | POLB | P06746 | 1/20 | 0.48 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.48 |
| ▸ | PPARA | Q07869 | 3/20 | 0.46 |
| ▸ | BID | P55957 | 3/20 | 0.46 |
| ▸ | MCL1 | Q07820 | 3/20 | 0.46 |
| ▸ | BCL2L1 | Q07817 | 2/20 | 0.46 |
| ▸ | BAK1 | Q16611 | 2/20 | 0.46 |
| ▸ | KAT8 | Q9H7Z6 | 2/20 | 0.46 |
| ▸ | PPARG | P37231 | 2/20 | 0.46 |
| ▸ | EP300 | Q09472 | 1/20 | 0.46 |
| ▸ | KAT2A | Q92830 | 1/20 | 0.46 |
| ▸ | KAT2B | Q92831 | 1/20 | 0.46 |
| ▸ | KAT5 | Q92993 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5161923 | 1.00 | TSHR (0.54) | TSHRALDH1A1LMNATP53CYP3A4 | |
| SCHEMBL27714335 | 1.00 | TSHR (0.54) | TSHRALDH1A1LMNATP53CYP3A4 | |
| SCHEMBL3677486 | 1.00 | TSHR (0.54) | TSHRALDH1A1LMNATP53CYP3A4 | |
| SCHEMBL150148 | 1.00 | TSHR (0.54) | TSHRALDH1A1LMNATP53CYP3A4 | |
| SCHEMBL9139754 | 0.97 | TSHR (0.54) | TSHRALDH1A1LMNATP53CYP3A4 | |
| SCHEMBL11153529 | 0.97 | TSHR (0.54) | TSHRALDH1A1LMNATP53CYP3A4 | |
| SCHEMBL11338437 | 0.97 | TSHR (0.50) | TSHRALDH1A1LMNATP53CYP3A4 | |
| SCHEMBL15632603 | 0.92 | ALDH1A1 (0.54) | TSHRALDH1A1LMNATP53CYP3A4 | |
| SCHEMBL11310948 | 0.92 | TSHR (0.50) | TSHRALDH1A1LMNATP53CYP3A4 | |
| SCHEMBL18489486 | 0.92 | TSHR (0.51) | TSHRALDH1A1LMNATP53CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4177172-A | EMULSIFIERS OF PARTIALLY HYDROLYSED POLYVINYL ACETATE, POLYVINYLPYRROLIDONE, OR VINYL ACETATE/VINYLPYRROLIDONE COPOLYMER | BAYER AKTIENGESELLSCHAFT (DE) | 1979-12-04 | — | — | US | disclosed |