Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11513636 | 0.90 | LMNA (0.33) | LMNA | |
| SCHEMBL11512615 | 0.89 | LMNA (0.32) | LMNA | |
| SCHEMBL11513759 | 0.88 | LMNA (0.31) | LMNA | |
| SCHEMBL11512434 | 0.88 | LMNA (0.31) | LMNA | |
| SCHEMBL11513641 | 0.88 | LMNA (0.31) | LMNA | |
| SCHEMBL11512442 | 0.88 | LMNA (0.31) | LMNA | |
| SCHEMBL11513208 | 0.88 | LMNA (0.31) | LMNA | |
| SCHEMBL11513321 | 0.88 | LMNA (0.31) | LMNA | |
| SCHEMBL11513202 | 0.88 | LMNA (0.31) | LMNA | |
| SCHEMBL11513329 | 0.88 | LMNA (0.31) | LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4138583-A | ANTICOAGULANTS, CARDIOVASCULAR DISORDERS, HYPOTENSIVE AGENTS | MILES LABORATORIES, INC. (US) | 1979-02-06 | — | — | US | disclosed |
| US-4138582-A | ANTICOAGULANTS, CARDIOVASCULAR DISORDERS, HYPOTENSIVE AGENTS | MILES LABORATORIES, INC. (US) | 1979-02-06 | — | — | US | disclosed |
| US-4066834-A | Cycloalkenyl analogues of prostaglandins E | MILES LABORATORIES, INC. (US) | 1978-01-03 | — | — | US | disclosed |