Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR4 | Q5NUL3 | 2/20 | 0.49 |
| ▸ | FFAR1 | O14842 | 2/20 | 0.49 |
| ▸ | ACACB | O00763 | 1/20 | 0.45 |
| ▸ | ACACA | Q13085 | 1/20 | 0.45 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.38 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.36 |
| ▸ | PTGFR | P43088 | 1/20 | 0.36 |
| ▸ | PTGER2 | P43116 | 1/20 | 0.36 |
| ▸ | FAAH | O00519 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | PTGER1 | P34995 | 1/20 | 0.34 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.34 |
| ▸ | PTGER3 | P43115 | 1/20 | 0.34 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.34 |
| ▸ | GSTK1 | Q9Y2Q3 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11512502 | 0.86 | FFAR4 (0.51) | FFAR4FFAR1ACACBACACATBXA2R | |
| SCHEMBL10728789 | 0.83 | FFAR4 (0.73) | FFAR4FFAR1FAAHALDH1A1PTPN1 | |
| SCHEMBL11515005 | 0.83 | FFAR4 (0.73) | FFAR4FFAR1FAAHALDH1A1PTPN1 | |
| SCHEMBL11515906 | 0.83 | FFAR4 (0.73) | FFAR4FFAR1FAAHALDH1A1PTPN1 | |
| SCHEMBL11603782 | 0.82 | FFAR4 (0.47) | FFAR4FFAR1ACACBACACAALOX5 | |
| SCHEMBL11620649 | 0.81 | FFAR4 (0.51) | FFAR4FFAR1ACACBACACAALOX5 | |
| SCHEMBL11516521 | 0.80 | FFAR4 (0.50) | FFAR4FFAR1ACACBACACAALOX5 | |
| SCHEMBL11515135 | 0.78 | MAPT (0.50) | FFAR4FFAR1TBXA2RPTGFRPTGER2 | |
| SCHEMBL11746247 | 0.78 | FFAR4 (0.51) | FFAR4FFAR1ACACBACACAALOX5 | |
| SCHEMBL11742346 | 0.78 | FFAR4 (0.47) | FFAR4FFAR1ACACBACACAALOX5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4155908-A | PSORIASIS, ANTICOAGULANTS | MERCK & CO., INC. (US) | 1979-05-22 | — | — | US | claimed |
| US-4155908-A | PSORIASIS, ANTICOAGULANTS | MERCK & CO., INC. (US) | 1979-05-22 | — | — | US | disclosed |
| US-4128564-A | 9-Thia- and oxothia- and 9-dioxothia-11,12-seco-prostaglandins | MERCK & CO., INC. (US) | 1978-12-05 | — | — | US | disclosed |
| US-4085125-A | 9-Thia-, 9-oxothia-, and 9-dioxothia-11,12-seco-prostaglandins and processes | MERCK & CO., INC. (US) | 1978-04-18 | — | — | US | disclosed |
| US-4066675-A | PSORIASIS, THROMBOSIS | MERCK & CO., INC. (US) | 1978-01-03 | — | — | US | disclosed |
| US-4018802-A | SKIN DISEASES, GROWTH HORMONE STIMULANTS, THROMBUS PREVENTION, IMMUNOLOGY | MERCK & CO., INC. (US) | 1977-04-19 | — | — | US | disclosed |