Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR4 | Q5NUL3 | 2/20 | 0.47 |
| ▸ | FFAR1 | O14842 | 2/20 | 0.47 |
| ▸ | ACACB | O00763 | 1/20 | 0.44 |
| ▸ | ACACA | Q13085 | 1/20 | 0.44 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.35 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.35 |
| ▸ | PTGFR | P43088 | 1/20 | 0.35 |
| ▸ | PTGER2 | P43116 | 1/20 | 0.35 |
| ▸ | GSTK1 | Q9Y2Q3 | 1/20 | 0.35 |
| ▸ | ENPEP | Q07075 | 1/20 | 0.35 |
| ▸ | FAAH | O00519 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.34 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11620649 | 0.86 | FFAR4 (0.51) | FFAR4FFAR1ACACBACACAALOX5 | |
| SCHEMBL11744959 | 0.85 | FFAR4 (0.54) | FFAR4FFAR1ACACBACACAALDH1A1 | |
| SCHEMBL11743888 | 0.81 | FFAR4 (0.56) | FFAR4FFAR1ACACBACACAALDH1A1 | |
| SCHEMBL11743577 | 0.81 | FFAR4 (0.75) | FFAR4FFAR1ALDH1A1PTPN1FAAH | |
| SCHEMBL11743880 | 0.81 | FFAR4 (0.75) | FFAR4FFAR1ALDH1A1PTPN1FAAH | |
| SCHEMBL11743581 | 0.81 | FFAR4 (0.75) | FFAR4FFAR1ALDH1A1PTPN1FAAH | |
| SCHEMBL11743835 | 0.81 | FFAR4 (0.75) | FFAR4FFAR1ALDH1A1PTPN1FAAH | |
| SCHEMBL11746247 | 0.80 | FFAR4 (0.51) | FFAR4FFAR1ACACBACACAALOX5 | |
| SCHEMBL11792952 | 0.80 | FFAR4 (0.44) | FFAR4FFAR1ACACBACACAALOX5 | |
| SCHEMBL11516521 | 0.79 | FFAR4 (0.50) | FFAR4FFAR1ACACBACACAALOX5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4055597-A | RENAL VASODILATORS | MERCK & CO., INC. (US) | 1977-10-25 | — | — | US | claimed |
| US-4055597-A | RENAL VASODILATORS | MERCK & CO., INC. (US) | 1977-10-25 | — | — | US | disclosed |