Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ATM | Q13315 | 1/20 | 0.66 |
| ▸ | CTSL | P07711 | 6/20 | 0.52 |
| ▸ | CTSS | P25774 | 1/20 | 0.52 |
| ▸ | TGM2 | P21980 | 1/20 | 0.52 |
| ▸ | RAB9A | P51151 | 2/20 | 0.49 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | HTT | P42858 | 1/20 | 0.47 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.47 |
| ▸ | NPC1 | O15118 | 1/20 | 0.47 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.47 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11066063 | 1.00 | ATM (0.66) | ATMCTSLCTSSTGM2RAB9A | |
| SCHEMBL10967450 | 0.90 | ATM (0.57) | ATMCTSLCTSSTGM2RAB9A | |
| SCHEMBL10967446 | 0.90 | ATM (0.54) | ATMCTSLCTSSTGM2RAB9A | |
| SCHEMBL11293241 | 0.90 | ATM (0.54) | ATMCTSLCTSSTGM2RAB9A | |
| SCHEMBL11216821 | 0.89 | ATM (0.53) | ATMCTSLTGM2RAB9AMAPT | |
| SCHEMBL11204903 | 0.88 | ATM (0.58) | ATMCTSLCTSSTGM2 | |
| SCHEMBL11533827 | 0.87 | SMN1; SMN2 (0.56) | ATMCTSLCTSSRAB9AMAPT | |
| SCHEMBL11692430 | 0.86 | ATM (0.49) | ATMCTSLTGM2RAB9ANPC1 | |
| SCHEMBL1362502 | 0.85 | ATM (0.77) | ATMCTSLCTSS | |
| SCHEMBL3255533 | 0.85 | ATM (0.77) | ATMCTSLCTSS |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4175185-A | ESTERIFICATION, IMINOHALOGENATION, ETHERIFICATION, HYDROLYSIS, DEESTERIFICATION | MEIJI SEIKA KAISHA LTD. (JP) | 1979-11-20 | — | — | US | disclosed |
| US-3998816-A | 7-[5-N-(n-Butoxyethoxy carbonyl and 2-chloroethoxy carbonyl)-amino] cephalosporins C | MEIJI SEIKA KAISHA, LTD. (JA) | 1976-12-21 | — | — | US | disclosed |