Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.32 |
| ▸ | MAPT | P10636 | 3/20 | 0.32 |
| ▸ | NPC1 | O15118 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | PKM | P14618 | 1/20 | 0.32 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.32 |
| ▸ | CASP1 | P29466 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
| ▸ | CASP7 | P55210 | 1/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
| ▸ | EGFR | P00533 | 1/20 | 0.31 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.31 |
| ▸ | ELANE | P08246 | 1/20 | 0.31 |
| ▸ | CES2 | O00748 | 1/20 | 0.30 |
| ▸ | CEPT1 | Q9Y6K0 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11512213 | 0.80 | PIK3CD (0.41) | MEN1KMT2AMAPTNPC1ALDH1A1 | |
| SCHEMBL11512392 | 0.75 | EGFR (0.33) | MEN1KMT2AKDM4EMAPTALDH1A1 | |
| SCHEMBL11513437 | 0.74 | TDP1 (0.49) | MEN1KMT2AKDM4EMAPTALDH1A1 | |
| SCHEMBL11514772 | 0.73 | MEN1 (0.33) | MEN1KMT2AMAPTNPC1RAB9A | |
| SCHEMBL30890176 | 0.73 | MEN1 (0.33) | MEN1KMT2AMAPTNPC1RAB9A | |
| SCHEMBL6111601 | 0.73 | MAPT (0.39) | MEN1KMT2ATSHRKDM4EMAPT | |
| SCHEMBL5540650 | 0.72 | ELANE (0.43) | MEN1KMT2ATSHRKDM4EMAPT | |
| SCHEMBL7108396 | 0.72 | ELANE (0.36) | MEN1KMT2AKDM4EMAPTNPC1 | |
| SCHEMBL11514781 | 0.72 | PSMB8 (0.37) | MEN1KMT2AKDM4EMAPTNPC1 | |
| SCHEMBL11330662 | 0.71 | GAA (0.36) | MEN1KMT2ATSHRMAPTNPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4146712-A | PROCESS FOR THE MANUFACTURE OF COUMARIN DYES | CIBA-GEIGY CORPORATION (US) | 1979-03-27 | — | — | US | disclosed |
| US-4064136-A | FROM A NITRILE, AN ALCOHOL AND ORTHO-SUBSTITUTED AROMATIC AMINE | CIBA-GEIGY AG (CH) | 1977-12-20 | — | — | US | disclosed |