SCHEMBL7108396

SCHEMBL7108396

N#CCc1nc2c(N)cccc2o1

nearest known ligand 0.36

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ELANE P08246 1/20 0.36
F2RL3 Q96RI0 2/20 0.34
MEN1 O00255 4/20 0.34
KMT2A Q03164 4/20 0.34
EGFR P00533 1/20 0.33
KDM4E B2RXH2 5/20 0.33
TDP1 Q9NUW8 3/20 0.33
LOXL2 Q9Y4K0 1/20 0.33
MAPT P10636 7/20 0.33
NPC1 O15118 3/20 0.33
RAB9A P51151 3/20 0.33
HSD17B10 Q99714 2/20 0.33
HIF1A Q16665 1/20 0.33
TP53 P04637 1/20 0.32
HTT P42858 1/20 0.32
GFER P55789 1/20 0.32
SMN1; SMN2 Q16637 1/20 0.32
PSMB8 P28062 1/20 0.31
ALDH1A1 P00352 2/20 0.31
ALOX15 P16050 2/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11512213 0.82 PIK3CD (0.41) ELANEF2RL3MEN1KMT2AEGFR
SCHEMBL11514772 0.81 MEN1 (0.33) ELANEMEN1KMT2AEGFRMAPT
SCHEMBL30890176 0.81 MEN1 (0.33) ELANEMEN1KMT2AEGFRMAPT
SCHEMBL11514781 0.81 PSMB8 (0.37) MEN1KMT2AEGFRKDM4ETDP1
SCHEMBL29236645 0.80 LOXL2 (0.40) ELANEF2RL3MEN1KMT2AKDM4E
SCHEMBL11513885 0.78 PIK3CD (0.44) MEN1KMT2AEGFRKDM4EMAPT
SCHEMBL1917749 0.78 ELANE (0.39) ELANEF2RL3MEN1KMT2AKDM4E
SCHEMBL11513386 0.77 MEN1 (0.35) MEN1KMT2AEGFRLOXL2MAPT
SCHEMBL7111564 0.76 ALDH1A1 (0.49) F2RL3MEN1KMT2AKDM4ETDP1
SCHEMBL1095484 0.75 MAPT (0.41) ELANEF2RL3MEN1KMT2AKDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1353222-A1 Photographic element containing azole couplers EASTMAN KODAK COMPANY (US) 2003-10-15 EP disclosed
US-6521397-B1 Support bearing light sensitive silver halide emulsion layer having associated such as 2-benzoazoacetoitrile derivative dye forming coupler; improved absorption maximum and color gamut EASTMAN KODAK COMPANY 2003-02-18 US disclosed