Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 8/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.56 |
| ▸ | MEN1 | O00255 | 1/20 | 0.56 |
| ▸ | MAPT | P10636 | 4/20 | 0.54 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.54 |
| ▸ | CYP3A4 | P08684 | 6/20 | 0.53 |
| ▸ | CYP2C19 | P33261 | 6/20 | 0.53 |
| ▸ | CYP2C9 | P11712 | 4/20 | 0.53 |
| ▸ | CYP2D6 | P10635 | 6/20 | 0.52 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.52 |
| ▸ | HTT | P42858 | 1/20 | 0.52 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.51 |
| ▸ | IDE | P14735 | 1/20 | 0.51 |
| ▸ | CLK4 | Q9HAZ1 | 4/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.49 |
| ▸ | POLB | P06746 | 1/20 | 0.49 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.49 |
| ▸ | PPARG | P37231 | 1/20 | 0.49 |
| ▸ | NR2E3 | Q9Y5X4 | 1/20 | 0.49 |
| ▸ | NCOR2 | Q9Y618 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11515727 | 0.86 | MEN1 (0.57) | CYP1A2KMT2AMEN1MAPTKDM4E | |
| SCHEMBL11648801 | 0.83 | MEN1 (0.59) | CYP1A2KMT2AMEN1MAPTKDM4E | |
| SCHEMBL11515259 | 0.83 | CYP1A2 (0.61) | CYP1A2KMT2AMEN1MAPTKDM4E | |
| SCHEMBL11651691 | 0.83 | MEN1 (0.53) | CYP1A2KMT2AMEN1MAPTKDM4E | |
| SCHEMBL11651088 | 0.82 | MEN1 (0.58) | CYP1A2KMT2AMEN1MAPTKDM4E | |
| SCHEMBL11517088 | 0.81 | MEN1 (0.51) | CYP1A2KMT2AMEN1MAPTKDM4E | |
| SCHEMBL11517093 | 0.81 | MEN1 (0.51) | CYP1A2KMT2AMEN1MAPTKDM4E | |
| SCHEMBL11514663 | 0.80 | MAPT (0.51) | CYP1A2KMT2AMEN1MAPTKDM4E | |
| SCHEMBL11514659 | 0.80 | MAPT (0.51) | CYP1A2KMT2AMEN1MAPTKDM4E | |
| SCHEMBL11652035 | 0.80 | MAPT (0.54) | CYP1A2KMT2AMEN1MAPTKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-RE30024-E | ANTIALLERGENS | STERLING DRUG INC. (US) | 1979-06-05 | — | — | US | disclosed |
| US-4118571-A | ANTIALLERGENS | STERLING DRUG INC. (US) | 1978-10-03 | — | — | US | disclosed |
| US-4086233-A | ANTIALLERGENS | STERLING DRUG INC. (US) | 1978-04-25 | — | — | US | disclosed |
| US-4032523-A | ANTIALLERGENS | STERLING DRUG INC. (US) | 1977-06-28 | — | — | US | disclosed |
| US-4018770-A | ANTIALLERGENS | STERLING DRUG INC. (US) | 1977-04-19 | — | — | US | disclosed |
| US-3992380-A | 5,8-Dihydro-5-oxo-2-(4-or 3-pyridinyl)pyrido[2,3-d]pyrimidine-6-carboxylic acids and esters | STERLING DRUG INC. (US) | 1976-11-16 | — | — | US | disclosed |