Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EP300 | Q09472 | 1/20 | 0.39 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 4/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.32 |
| ▸ | FASN | P49327 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | GMNN | O75496 | 1/20 | 0.31 |
| ▸ | USP2 | O75604 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.31 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.31 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.31 |
| ▸ | APEX1 | P27695 | 1/20 | 0.31 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.31 |
| ▸ | RECQL | P46063 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18649678 | 0.82 | PTPN1 (0.45) | EP300PTPN1TSHRALDH1A1FASN | |
| SCHEMBL13825221 | 0.80 | TRPA1 (0.48) | EP300PTPN1TSHRALDH1A1FASN | |
| SCHEMBL30698180 | 0.80 | TRPA1 (0.48) | EP300PTPN1TSHRALDH1A1FASN | |
| SCHEMBL23087045 | 0.80 | TRPA1 (0.48) | EP300PTPN1TSHRALDH1A1FASN | |
| SCHEMBL30924809 | 0.80 | TSHR (0.50) | EP300PTPN1TSHRALDH1A1FASN | |
| SCHEMBL23087043 | 0.80 | TRPA1 (0.48) | EP300PTPN1TSHRALDH1A1FASN | |
| SCHEMBL28912640 | 0.80 | TRPA1 (0.48) | EP300PTPN1TSHRALDH1A1FASN | |
| SCHEMBL8700013 | 0.78 | EP300 (0.45) | EP300PTPN1TSHRMEN1CYP3A4 | |
| SCHEMBL8700010 | 0.78 | EP300 (0.45) | EP300PTPN1TSHRMEN1CYP3A4 | |
| SCHEMBL20385078 | 0.77 | EP300 (0.41) | EP300PTPN1TSHRALDH1A1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4169199-A | Precursors for prostaglandin analogue and process for preparing the same | SAGAMI CHEMICAL RESEARCH CENTER (JP) | 1979-09-25 | — | — | US | disclosed |