Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA12 | O43570 | 1/20 | 0.50 |
| ▸ | CA1 | P00915 | 1/20 | 0.50 |
| ▸ | CA2 | P00918 | 1/20 | 0.50 |
| ▸ | CA9 | Q16790 | 1/20 | 0.50 |
| ▸ | TSHR | P16473 | 2/20 | 0.42 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | PPARD | Q03181 | 2/20 | 0.38 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17764806 | 0.92 | CES2 (0.46) | CA12CA1CA2CA9TSHR | |
| SCHEMBL27546804 | 0.91 | CA1 (0.47) | CA12CA1CA2CA9TSHR | |
| SCHEMBL11514054 | 0.90 | CA12 (0.48) | CA12CA1CA2CA9TSHR | |
| SCHEMBL20247639 | 0.90 | CA12 (0.43) | CA12CA1CA2CA9TSHR | |
| SCHEMBL2984011 | 0.86 | CA12 (0.45) | CA12CA1CA2CA9TSHR | |
| SCHEMBL2994641 | 0.85 | CA12 (0.48) | CA12CA1CA2CA9TSHR | |
| SCHEMBL2304211 | 0.84 | PPARD (0.46) | CA12CA1CA2CA9TSHR | |
| SCHEMBL7916562 | 0.82 | CA12 (0.42) | CA12CA1CA2CA9TSHR | |
| SCHEMBL7860633 | 0.79 | CA12 (0.40) | CA12CA1CA2CA9TSHR | |
| SCHEMBL1107421 | 0.76 | CA12 (0.45) | CA12CA1CA2CA9TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4164394-A | USING AN ACYLPHOSPHONATE AS ACTIVATOR | FMC CORPORATION (US) | 1979-08-14 | — | — | US | disclosed |