Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.42 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | ATM | Q13315 | 1/20 | 0.39 |
| ▸ | CTSK | P43235 | 3/20 | 0.37 |
| ▸ | CTSL | P07711 | 2/20 | 0.37 |
| ▸ | CTSS | P25774 | 2/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.36 |
| ▸ | CTSB | P07858 | 1/20 | 0.35 |
| ▸ | CTSH | P09668 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11695044 | 1.00 | KMT2A (0.42) | KMT2AMEN1HTTATMCTSK | |
| SCHEMBL11130093 | 0.81 | HTT (0.44) | KMT2AMEN1HTTCYP3A4CYP2D6 | |
| SCHEMBL1994993 | 0.81 | ATM (0.48) | KMT2AHTTATMCTSLCTSS | |
| SCHEMBL1994994 | 0.81 | ATM (0.48) | KMT2AHTTATMCTSLCTSS | |
| SCHEMBL11162533 | 0.81 | MEN1 (0.40) | KMT2AMEN1HTTATMCTSK | |
| SCHEMBL10640347 | 0.79 | ATM (0.54) | KMT2AMEN1HTTATMCTSK | |
| SCHEMBL10493249 | 0.79 | ATM (0.54) | KMT2AMEN1HTTATMCTSK | |
| SCHEMBL9090282 | 0.79 | CTSL (0.56) | ATMCTSKCTSLCTSSCYP1A2 | |
| SCHEMBL9087031 | 0.79 | CTSL (0.56) | ATMCTSKCTSLCTSSCYP1A2 | |
| SCHEMBL10857063 | 0.78 | ATM (0.44) | KMT2AMEN1HTTATMCTSK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4175185-A | ESTERIFICATION, IMINOHALOGENATION, ETHERIFICATION, HYDROLYSIS, DEESTERIFICATION | MEIJI SEIKA KAISHA LTD. (JP) | 1979-11-20 | — | — | US | disclosed |