SCHEMBL11514979

SCHEMBL11514979

Nc1cccc2c(C(=O)O)cc(C(=O)O)cc12

nearest known ligand 0.48

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CDC25B P30305 5/20 0.48
CDC25A P30304 1/20 0.48
CDC25C P30307 1/20 0.48
MMP2 P08253 1/20 0.47
NSD2 O96028 2/20 0.43
PTPN1 P18031 1/20 0.42
IDO1 P14902 1/20 0.42
HSD17B10 Q99714 3/20 0.41
TDP1 Q9NUW8 3/20 0.41
HPGD P15428 2/20 0.41
TSHR P16473 2/20 0.41
ALDH1A1 P00352 2/20 0.41
CYP3A4 P08684 1/20 0.41
TTR P02766 1/20 0.41
CYP2C9 P11712 1/20 0.41
ALOX12 P18054 1/20 0.41
ATIC P31939 1/20 0.41
KDM4E B2RXH2 3/20 0.40
KMT2A Q03164 2/20 0.40
NR4A1 P22736 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9220619 0.85 CDC25B (0.54) CDC25BCDC25ACDC25CMMP2NSD2
SCHEMBL31401767 0.83 PTPN1 (0.55) CDC25BCDC25APTPN1HSD17B10HPGD
SCHEMBL28651 0.83 PTPN1 (0.55) CDC25BCDC25APTPN1HSD17B10HPGD
Hydrochloric Acid SCHEMBL7538741 0.81 PTPN1 (0.53) CDC25BCDC25APTPN1HSD17B10HPGD
SCHEMBL29549315 0.79 CDC25B (0.64) CDC25BCDC25ACDC25CMMP2NSD2
SCHEMBL689824 0.79 CDC25B (0.64) CDC25BCDC25ACDC25CMMP2NSD2
Hydrochloric Acid SCHEMBL10447811 0.77 CDC25B (0.62) CDC25BCDC25ACDC25CMMP2NSD2
Hydrochloric Acid SCHEMBL11552292 0.77 CDC25B (0.62) CDC25BCDC25ACDC25CMMP2NSD2
SCHEMBL29659433 0.76 CA12 (0.48) CDC25BCDC25APTPN1HSD17B10TDP1
SCHEMBL335300 0.76 CA12 (0.48) CDC25BCDC25APTPN1HSD17B10TDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4159379-A Dispersion dyestuffs of the naphtholactam series CIBA-GEIGY AG (CH) 1979-06-26 US disclosed