Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | OPRM1 | P35372 | 3/20 | 0.40 |
| ▸ | OPRL1 | P41146 | 3/20 | 0.40 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.39 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.39 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.39 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | ATAD2 | Q6PL18 | 1/20 | 0.36 |
| ▸ | CECR2 | Q9BXF3 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11516137 | 0.84 | TSHR (0.51) | TSHRKMT2AHTTLMNAADRA1D | |
| SCHEMBL11512605 | 0.84 | TSHR (0.51) | TSHRKMT2AHTTLMNAOPRM1 | |
| SCHEMBL11516159 | 0.82 | TSHR (0.63) | TSHRKMT2AHTTLMNAOPRM1 | |
| SCHEMBL11512354 | 0.82 | HTT (0.70) | TSHRHTTLMNASMN1; SMN2ALDH1A1 | |
| SCHEMBL11243429 | 0.82 | TSHR (0.56) | TSHRKMT2AHTTLMNAADRA1D | |
| SCHEMBL13451422 | 0.81 | HTT (0.59) | TSHRKMT2AHTTLMNAPIK3CD | |
| SCHEMBL21389409 | 0.79 | TSHR (0.46) | TSHRKMT2AHTTLMNAADRA1D | |
| SCHEMBL24795282 | 0.79 | GAA (0.45) | TSHRKMT2AHTTADRA1DADRA1A | |
| SCHEMBL11514599 | 0.79 | TSHR (0.46) | TSHRHTTLMNAADRA1DADRA1A | |
| SCHEMBL2036528 | 0.78 | TSHR (0.59) | TSHRKMT2AHTTLMNAPIK3CD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4162325-A | PHARMACEUTICAL ACTIVITY ON THE MNEMIC PROCESSES | UCB, SOCIETE ANONYME (BE) | 1979-07-24 | — | — | US | disclosed |