Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | CA12 | O43570 | 1/20 | 0.43 |
| ▸ | CA1 | P00915 | 1/20 | 0.43 |
| ▸ | CA2 | P00918 | 1/20 | 0.43 |
| ▸ | CA9 | Q16790 | 1/20 | 0.43 |
| ▸ | TP53 | P04637 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.40 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.40 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | PKM | P14618 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.38 |
| ▸ | PDK1 | Q15118 | 1/20 | 0.38 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.38 |
| ▸ | PDK3 | Q15120 | 1/20 | 0.38 |
| ▸ | PDK4 | Q16654 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL668453 | 0.87 | TSHR (0.56) | TSHRTP53LMNAADRA1DADRA1A | |
| SCHEMBL11514068 | 0.83 | LMNA (0.47) | TSHRLMNAADRA1DADRA1AADRA1B | |
| SCHEMBL11512605 | 0.82 | TSHR (0.51) | TSHRLMNAADRA1DADRA1AADRA1B | |
| SCHEMBL11516137 | 0.82 | TSHR (0.51) | TSHRLMNAADRA1DADRA1AADRA1B | |
| SCHEMBL6528311 | 0.82 | TSHR (0.50) | TSHRLMNAADRA1DADRA1AADRA1B | |
| SCHEMBL9821321 | 0.81 | TSHR (0.50) | TSHRTP53LMNAADRA1DADRA1A | |
| SCHEMBL11516159 | 0.81 | TSHR (0.63) | TSHRCA12CA1CA2CA9 | |
| SCHEMBL6495319 | 0.81 | TSHR (0.49) | TSHRLMNAADRA1DADRA1AADRA1B | |
| SCHEMBL11243429 | 0.81 | TSHR (0.56) | TSHRLMNAADRA1DADRA1AADRA1B | |
| SCHEMBL21389414 | 0.80 | ADRA1D (0.45) | TSHRTP53LMNAADRA1DADRA1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4162325-A | PHARMACEUTICAL ACTIVITY ON THE MNEMIC PROCESSES | UCB, SOCIETE ANONYME (BE) | 1979-07-24 | — | — | US | disclosed |