SCHEMBL11515971

SCHEMBL11515971

N#C/C(C(=O)O)=C(/N)c1ccnc(-c2ccncc2)n1

nearest known ligand 0.39

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
L3MBTL1 Q9Y468 2/20 0.39
RXFP1 Q9HBX9 1/20 0.39
XDH P47989 6/20 0.38
NEK2 P51955 1/20 0.37
PLK1 P53350 1/20 0.37
POLB P06746 1/20 0.37
ATM Q13315 1/20 0.35
LMNA P02545 1/20 0.35
ALDH1A1 P00352 1/20 0.35
KDM4E B2RXH2 1/20 0.35
MAP4K4 O95819 1/20 0.35
MYC P01106 1/20 0.35
IDE P14735 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11515732 0.91 NEK2 (0.41) L3MBTL1RXFP1XDHNEK2PLK1
SCHEMBL11663142 0.91 NEK2 (0.41) L3MBTL1RXFP1XDHNEK2PLK1
SCHEMBL11515662 0.77 POLB (0.40) L3MBTL1RXFP1XDHPOLBATM
SCHEMBL11515178 0.77 POLB (0.40) L3MBTL1RXFP1XDHPOLBATM
SCHEMBL13726855 0.77 L3MBTL1 (0.51) L3MBTL1RXFP1POLBATMLMNA
SCHEMBL11517082 0.73 POLB (0.54) L3MBTL1RXFP1POLBATMLMNA
SCHEMBL11517079 0.73 POLB (0.54) L3MBTL1RXFP1POLBATMLMNA
SCHEMBL11515582 0.73 POLB (0.41) L3MBTL1RXFP1POLBATMLMNA
SCHEMBL11516769 0.72 RECQL (0.38) L3MBTL1RXFP1XDHNEK2PLK1
SCHEMBL29961369 0.68 SCN9A (0.47) XDHKDM4EMAP4K4MYC

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-RE30024-E ANTIALLERGENS STERLING DRUG INC. (US) 1979-06-05 US disclosed