Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.33 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.33 |
| ▸ | PGR | P06401 | 1/20 | 0.33 |
| ▸ | CYP19A1 | P11511 | 7/20 | 0.32 |
| ▸ | OR51E2 | Q9H255 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11516496 | 1.00 | LMNA (0.33) | LMNANR1I2NR3C1PGRCYP19A1 | |
| SCHEMBL11747968 | 0.90 | LMNA (0.31) | LMNANR1I2NR3C1PGRCYP19A1 | |
| SCHEMBL11747974 | 0.90 | LMNA (0.31) | LMNANR1I2NR3C1PGRCYP19A1 | |
| SCHEMBL11744396 | 0.89 | CYP19A1 (0.30) | CYP19A1 | |
| SCHEMBL11744390 | 0.89 | CYP19A1 (0.30) | CYP19A1 | |
| SCHEMBL11744999 | 0.86 | — | — | |
| SCHEMBL11747464 | 0.86 | CYP19A1 (0.31) | CYP19A1 | |
| SCHEMBL11517535 | 0.86 | — | — | |
| SCHEMBL11744269 | 0.86 | CYP19A1 (0.32) | CYP19A1 | |
| SCHEMBL11744276 | 0.86 | CYP19A1 (0.32) | CYP19A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4058539-A | 4,6,8(14)-Triene steroids | STEELE CHEMICALS CO. LTD. (CA) | 1977-11-15 | — | — | US | claimed |
| US-4134891-A | 14-Functionalized 8,19-oxido steroids and processes for preparation thereof | STEELE CHEMICALS CO. LTD. (CA) | 1979-01-16 | — | — | US | disclosed |
| US-4102884-A | TREATING A 3,14-DIHYDROXY-CARDENOLIDE WITH OXYGEN AND N-BROMOACETAMIDE IN THE PRESENCE OF PLATINUM, THEN WITH ETHANEDITHIOL, RANEY NICKEL | STEELE CHEMICALS CO. LTD. (CA) | 1978-07-25 | — | — | US | disclosed |
| US-4102883-A | 19,8-Lactone steroid derivatives and processes of preparation thereof | STEELE CHEMICALS CO. LTD. (CA) | 1978-07-25 | — | — | US | disclosed |
| US-4058539-A | 4,6,8(14)-Triene steroids | STEELE CHEMICALS CO. LTD. (CA) | 1977-11-15 | — | — | US | disclosed |