Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.51 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.50 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.48 |
| ▸ | ATM | Q13315 | 1/20 | 0.48 |
| ▸ | IDE | P14735 | 2/20 | 0.47 |
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.38 |
| ▸ | NFKB2 | Q00653 | 2/20 | 0.38 |
| ▸ | RELA | Q04206 | 2/20 | 0.38 |
| ▸ | FOS | P01100 | 1/20 | 0.38 |
| ▸ | JUN | P05412 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 3/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11516743 | 1.00 | POLB (0.51) | POLBL3MBTL1RXFP1ALDH1A1ATM | |
| SCHEMBL11517082 | 0.84 | POLB (0.54) | POLBL3MBTL1RXFP1ALDH1A1ATM | |
| SCHEMBL11517079 | 0.84 | POLB (0.54) | POLBL3MBTL1RXFP1ALDH1A1ATM | |
| SCHEMBL11514757 | 0.80 | DHODH (0.47) | POLBL3MBTL1RXFP1ALDH1A1ATM | |
| SCHEMBL11514763 | 0.80 | DHODH (0.47) | POLBL3MBTL1RXFP1ALDH1A1ATM | |
| SCHEMBL11513877 | 0.79 | POLB (0.62) | POLBL3MBTL1RXFP1ALDH1A1ATM | |
| SCHEMBL11515727 | 0.77 | MEN1 (0.57) | POLBL3MBTL1RXFP1ALDH1A1ATM | |
| SCHEMBL11762471 | 0.76 | NPC1 (0.49) | L3MBTL1RXFP1ALDH1A1SMN1; SMN2KDM4E | |
| SCHEMBL11517093 | 0.76 | MEN1 (0.51) | POLBL3MBTL1RXFP1ALDH1A1ATM | |
| SCHEMBL11517088 | 0.76 | MEN1 (0.51) | POLBL3MBTL1RXFP1ALDH1A1ATM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-RE30024-E | ANTIALLERGENS | STERLING DRUG INC. (US) | 1979-06-05 | — | — | US | disclosed |
| US-4118571-A | ANTIALLERGENS | STERLING DRUG INC. (US) | 1978-10-03 | — | — | US | disclosed |
| US-4086233-A | ANTIALLERGENS | STERLING DRUG INC. (US) | 1978-04-25 | — | — | US | disclosed |
| US-4032523-A | ANTIALLERGENS | STERLING DRUG INC. (US) | 1977-06-28 | — | — | US | disclosed |
| US-4018770-A | ANTIALLERGENS | STERLING DRUG INC. (US) | 1977-04-19 | — | — | US | disclosed |