Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.62 |
| ▸ | ATM | Q13315 | 1/20 | 0.58 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.58 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.58 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.58 |
| ▸ | IDE | P14735 | 2/20 | 0.57 |
| ▸ | LMNA | P02545 | 2/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.46 |
| ▸ | FOS | P01100 | 1/20 | 0.44 |
| ▸ | JUN | P05412 | 1/20 | 0.44 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.44 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.44 |
| ▸ | RELA | Q04206 | 1/20 | 0.44 |
| ▸ | NAMPT | P43490 | 1/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11517421 | 0.87 | POLB (0.54) | POLBATMALDH1A1L3MBTL1RXFP1 | |
| SCHEMBL11514857 | 0.81 | POLB (0.69) | POLBATMALDH1A1L3MBTL1RXFP1 | |
| SCHEMBL10919867 | 0.80 | CYP1A2 (0.69) | POLBATMALDH1A1L3MBTL1RXFP1 | |
| SCHEMBL11696189 | 0.80 | POLB (0.60) | POLBATMALDH1A1L3MBTL1RXFP1 | |
| SCHEMBL11516739 | 0.79 | POLB (0.51) | POLBATMALDH1A1L3MBTL1RXFP1 | |
| SCHEMBL11516743 | 0.79 | POLB (0.51) | POLBATMALDH1A1L3MBTL1RXFP1 | |
| SCHEMBL15976898 | 0.79 | KMT2A (0.58) | POLBALDH1A1SMN1; SMN2KDM4ECYP1A2 | |
| SCHEMBL11515727 | 0.79 | MEN1 (0.57) | POLBATMALDH1A1L3MBTL1RXFP1 | |
| SCHEMBL11516097 | 0.79 | POLB (0.50) | POLBATMALDH1A1L3MBTL1RXFP1 | |
| SCHEMBL11516091 | 0.79 | POLB (0.50) | POLBATMALDH1A1L3MBTL1RXFP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-RE30024-E | ANTIALLERGENS | STERLING DRUG INC. (US) | 1979-06-05 | — | — | US | disclosed |
| US-4118571-A | ANTIALLERGENS | STERLING DRUG INC. (US) | 1978-10-03 | — | — | US | disclosed |
| US-4086233-A | ANTIALLERGENS | STERLING DRUG INC. (US) | 1978-04-25 | — | — | US | disclosed |
| US-4053475-A | ANTI-ALLERGIC AGENTS | STERLING DRUG INC. (US) | 1977-10-11 | — | — | US | disclosed |
| US-4032523-A | ANTIALLERGENS | STERLING DRUG INC. (US) | 1977-06-28 | — | — | US | disclosed |
| US-4018770-A | ANTIALLERGENS | STERLING DRUG INC. (US) | 1977-04-19 | — | — | US | disclosed |
| US-4008235-A | ANTIALLERGIC | STERLING DRUG INC. (US) | 1977-02-15 | — | — | US | disclosed |