Known targets — ChEMBL curated mechanism
ACHEADRA1AADRA1BADRA1DADRA2AADRA2BADRA2CADRB1ADRB2ADRB3APH1AAPH1BCHRM2CHRM3EZH2GRIN2AHTR1AHTR1BHTR1DHTR1FHTR3ANCSTNP2RY12PSEN1PSEN2PSENENSIGMAR1SLC6A2SLC6A3SLC6A4
The experimentally established mechanism targets of Bromide. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12955470 | 0.97 | — | — | |
| SCHEMBL2246459 | 0.97 | — | — | |
| SCHEMBL2246463 | 0.97 | — | — | |
| Hydrochloric Acid SCHEMBL15792149 | 0.95 | — | — | |
| Hydrochloric Acid SCHEMBL22979248 | 0.95 | — | — | |
| Hydrochloric Acid SCHEMBL15792147 | 0.95 | — | — | |
| Phosphonic Acid SCHEMBL11035163 | 0.89 | SLC15A1 (0.40) | — | |
| SCHEMBL11034167 | 0.87 | SLC15A1 (0.39) | — | |
| Bromide SCHEMBL11517257 | 0.85 | DPP4 (0.44) | — | |
| Bromide SCHEMBL10957448 | 0.83 | DPP4 (0.42) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4176116-A | ELASTASE ENZYME INHIBITORS | HOFFMANN-LA ROCHE INC. (US) | 1979-11-27 | — | — | US | disclosed |