Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.45 |
| ▸ | GAA | P10253 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.45 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.45 |
| ▸ | KCNJ11 | Q14654 | 6/20 | 0.45 |
| ▸ | ABCC9 | O60706 | 1/20 | 0.41 |
| ▸ | ABCC8 | Q09428 | 1/20 | 0.41 |
| ▸ | KCNJ8 | Q15842 | 1/20 | 0.41 |
| ▸ | NCEH1 | Q6PIU2 | 1/20 | 0.41 |
| ▸ | G6PD | P11413 | 1/20 | 0.41 |
| ▸ | SLC40A1 | Q9NP59 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | SOAT2 | O75908 | 1/20 | 0.40 |
| ▸ | SOAT1 | P35610 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21143063 | 0.80 | ALDH1A1 (0.39) | LMNAKMT2ACYP1A2CYP3A4GAA | |
| SCHEMBL6374171 | 0.80 | TSHR (0.48) | KMT2ACYP1A2CYP3A4GAACYP2C19 | |
| SCHEMBL11116162 | 0.80 | CYP1A2 (0.46) | CYP1A2CYP3A4GAAMAPTCYP2C19 | |
| SCHEMBL25860107 | 0.78 | ALDH1A1 (0.41) | LMNAKMT2ACYP1A2CYP2C19KCNJ11 | |
| SCHEMBL8845511 | 0.77 | KMT2A (0.68) | LMNAKMT2ASMN1; SMN2SOAT2SOAT1 | |
| SCHEMBL11517897 | 0.77 | MEN1 (0.47) | KMT2AGAAKCNJ11ABCC9ABCC8 | |
| Hydrogen Peroxide SCHEMBL8610670 | 0.75 | TSHR (0.52) | CYP1A2CYP3A4GAAMAPTCYP2C19 | |
| SCHEMBL248045 | 0.75 | KDM4E (0.53) | KMT2ACYP1A2GAACYP2C19NCEH1 | |
| SCHEMBL7369757 | 0.74 | MAPT (0.51) | KMT2ACYP1A2CYP3A4MAPTCYP2C19 | |
| SCHEMBL7372118 | 0.74 | ALDH1A1 (0.50) | LMNAKMT2ANCEH1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4158051-A | DIMETHYL DIBROMODICHLOROETHYL PHOSPHATE, NONVOLATILE CARBAMATE | A. H. ROBINS COMPANY, INC. (US) | 1979-06-12 | — | — | US | disclosed |