Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.37 |
| ▸ | NPC1 | O15118 | 3/20 | 0.37 |
| ▸ | RAB9A | P51151 | 3/20 | 0.37 |
| ▸ | MITF | O75030 | 2/20 | 0.37 |
| ▸ | PAX8 | Q06710 | 2/20 | 0.37 |
| ▸ | MEN1 | O00255 | 2/20 | 0.37 |
| ▸ | KDM1A | O60341 | 1/20 | 0.35 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 4/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
| ▸ | FASN | P49327 | 1/20 | 0.35 |
| ▸ | JAK2 | O60674 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | NCOA1 | Q15788 | 1/20 | 0.34 |
| ▸ | NCOA3 | Q9Y6Q9 | 1/20 | 0.34 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11521080 | 1.00 | KDM4E (0.38) | KDM4EALDH1A1KMT2ASMN1; SMN2NPC1 | |
| SCHEMBL11516820 | 0.94 | ALDH1A1 (0.38) | KDM4EALDH1A1KMT2ASMN1; SMN2NPC1 | |
| SCHEMBL11523040 | 0.91 | KDM4E (0.38) | KDM4EALDH1A1KMT2ASMN1; SMN2NPC1 | |
| SCHEMBL11519690 | 0.86 | SMN1; SMN2 (0.44) | KDM4EALDH1A1KMT2ASMN1; SMN2NPC1 | |
| SCHEMBL11456609 | 0.84 | ALDH1A1 (0.39) | KDM4EALDH1A1KMT2ASMN1; SMN2NPC1 | |
| SCHEMBL11446936 | 0.84 | ALDH1A1 (0.38) | KDM4EALDH1A1KMT2ASMN1; SMN2NPC1 | |
| SCHEMBL11454494 | 0.84 | KDM4E (0.39) | KDM4EALDH1A1KMT2ASMN1; SMN2NPC1 | |
| SCHEMBL11520324 | 0.82 | KDM4E (0.38) | KDM4EALDH1A1KMT2ASMN1; SMN2NPC1 | |
| SCHEMBL11465733 | 0.82 | ALDH1A1 (0.41) | KDM4EALDH1A1KMT2ASMN1; SMN2NPC1 | |
| SCHEMBL11446728 | 0.82 | ALDH1A1 (0.40) | KDM4EALDH1A1KMT2ASMN1; SMN2NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4148913-A | ANTIDEPRESSANTS | THE UPJOHN COMPANY (US) | 1979-04-10 | — | — | US | claimed |
| US-4148913-A | ANTIDEPRESSANTS | THE UPJOHN COMPANY (US) | 1979-04-10 | — | — | US | disclosed |