Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.68 |
| ▸ | BLM | P54132 | 1/20 | 0.54 |
| ▸ | PTPN1 | P18031 | 3/20 | 0.52 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 2/20 | 0.35 |
| ▸ | PTPN2 | P17706 | 1/20 | 0.35 |
| ▸ | CDC25B | P30305 | 1/20 | 0.35 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.34 |
| ▸ | GBA1 | P04062 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2350877 | 1.00 | LMNA (0.68) | LMNABLMPTPN1ALOX15MEN1 | |
| SCHEMBL95738 | 1.00 | LMNA (0.68) | LMNABLMPTPN1ALOX15MEN1 | |
| SCHEMBL2735604 | 1.00 | LMNA (0.68) | LMNABLMPTPN1ALOX15MEN1 | |
| SCHEMBL2352413 | 1.00 | LMNA (0.68) | LMNABLMPTPN1ALOX15MEN1 | |
| SCHEMBL2351564 | 1.00 | LMNA (0.68) | LMNABLMPTPN1ALOX15MEN1 | |
| SCHEMBL11753530 | 1.00 | LMNA (0.68) | LMNABLMPTPN1ALOX15MEN1 | |
| SCHEMBL27965 | 1.00 | LMNA (0.68) | LMNABLMPTPN1ALOX15MEN1 | |
| SCHEMBL11032494 | 1.00 | LMNA (0.68) | LMNABLMPTPN1ALOX15MEN1 | |
| SCHEMBL8846723 | 1.00 | LMNA (0.68) | LMNABLMPTPN1ALOX15MEN1 | |
| SCHEMBL95500 | 1.00 | LMNA (0.68) | LMNABLMPTPN1ALOX15MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4175139-A | Hypertension treating agent containing polyprenyl alcohol | EISAI CO. LTD. (JP) | 1979-11-20 | — | — | US | disclosed |