SCHEMBL11518330

SCHEMBL11518330

CCOC(=O)C(S)C(=O)O

nearest known ligand 0.43

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 4/20 0.43
HSD17B10 Q99714 3/20 0.42
LMNA P02545 2/20 0.42
ALOX15 P16050 2/20 0.40
MGAM O43451 1/20 0.40
GAA P10253 1/20 0.40
SI P14410 1/20 0.40
MGAM2 Q2M2H8 1/20 0.40
SOAT1 P35610 1/20 0.40
PIN1 Q13526 1/20 0.38
HCAR2 Q8TDS4 1/20 0.38
MEN1 O00255 2/20 0.37
KMT2A Q03164 2/20 0.37
NPC1 O15118 1/20 0.37
TRPA1 O75762 1/20 0.37
CPB2 Q96IY4 1/20 0.36
RNPEP Q9H4A4 1/20 0.36
MMP8 P22894 1/20 0.35
HPGD P15428 2/20 0.35
TDP1 Q9NUW8 2/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27688951 0.84 ALDH1A1 (0.48) ALDH1A1HSD17B10LMNAALOX15MGAM
SCHEMBL11470638 0.78 SOAT1 (0.44) ALDH1A1HSD17B10LMNAALOX15MGAM
SCHEMBL11753379 0.78 ALDH1A1 (0.42) ALDH1A1HSD17B10LMNAALOX15MGAM
SCHEMBL28765547 0.78 ALDH1A1 (0.52) ALDH1A1HSD17B10LMNAALOX15MGAM
SCHEMBL6421189 0.76 ALDH1A1 (0.44) ALDH1A1HSD17B10LMNAALOX15MGAM
SCHEMBL6421193 0.76 ALDH1A1 (0.40) ALDH1A1HSD17B10LMNAALOX15MGAM
SCHEMBL2029534 0.76
SCHEMBL4654662 0.76 ALDH1A1 (0.50) ALDH1A1HSD17B10LMNAALOX15MGAM
SCHEMBL11451537 0.75 ALDH1A1 (0.39) ALDH1A1HSD17B10LMNAALOX15MGAM
SCHEMBL5374208 0.74

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4155996-A PESTICIDES ROUSSEL UCLAF (FR) 1979-05-22 US disclosed