Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TP53 | P04637 | 1/20 | 0.60 |
| ▸ | NPC1 | O15118 | 1/20 | 0.59 |
| ▸ | JAK2 | O60674 | 1/20 | 0.59 |
| ▸ | RAB9A | P51151 | 1/20 | 0.59 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.59 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.58 |
| ▸ | GLA | P06280 | 1/20 | 0.58 |
| ▸ | TSHR | P16473 | 1/20 | 0.58 |
| ▸ | LTB4R2 | Q9NPC1 | 8/20 | 0.55 |
| ▸ | CES2 | O00748 | 2/20 | 0.50 |
| ▸ | CES1 | P23141 | 2/20 | 0.50 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.49 |
| ▸ | MEN1 | O00255 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17439411 | 1.00 | TP53 (0.60) | TP53NPC1JAK2RAB9APAX8 | |
| SCHEMBL17333743 | 0.93 | TP53 (0.64) | TP53NPC1JAK2RAB9APAX8 | |
| SCHEMBL1115056 | 0.90 | ALDH1A1 (0.58) | TP53NPC1JAK2RAB9APAX8 | |
| SCHEMBL1114803 | 0.90 | ALDH1A1 (0.58) | TP53NPC1JAK2RAB9APAX8 | |
| SCHEMBL12679904 | 0.89 | ALDH1A1 (0.56) | TP53NPC1JAK2RAB9APAX8 | |
| SCHEMBL29266757 | 0.89 | NPC1 (0.75) | TP53NPC1JAK2RAB9APAX8 | |
| SCHEMBL12679850 | 0.89 | ALDH1A1 (0.56) | TP53NPC1JAK2RAB9APAX8 | |
| SCHEMBL1114818 | 0.88 | ALDH1A1 (0.59) | TP53NPC1JAK2RAB9APAX8 | |
| SCHEMBL9666989 | 0.87 | TP53 (0.57) | TP53NPC1JAK2RAB9APAX8 | |
| SCHEMBL4740473 | 0.87 | TP53 (0.57) | TP53NPC1JAK2RAB9APAX8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4171975-A | MAGENTA COUPLER AND AN AMIDE | KONISHIROKU PHOTO INDUSTRY CO., LTD. (JP) | 1979-10-23 | — | — | US | disclosed |