Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TYR | P14679 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 3/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.35 |
| ▸ | PREP | P48147 | 1/20 | 0.33 |
| ▸ | PTGS2 | P35354 | 3/20 | 0.33 |
| ▸ | LMNA | P02545 | 2/20 | 0.32 |
| ▸ | NUAK1 | O60285 | 1/20 | 0.32 |
| ▸ | IGF1R | P08069 | 1/20 | 0.32 |
| ▸ | MET | P08581 | 1/20 | 0.32 |
| ▸ | PIM1 | P11309 | 1/20 | 0.32 |
| ▸ | SRC | P12931 | 1/20 | 0.32 |
| ▸ | AXL | P30530 | 1/20 | 0.32 |
| ▸ | AKT1 | P31749 | 1/20 | 0.32 |
| ▸ | KDR | P35968 | 1/20 | 0.32 |
| ▸ | NEK2 | P51955 | 1/20 | 0.32 |
| ▸ | PLK1 | P53350 | 1/20 | 0.32 |
| ▸ | PTK2 | Q05397 | 1/20 | 0.32 |
| ▸ | PKN1 | Q16512 | 1/20 | 0.32 |
| ▸ | AURKB | Q96GD4 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28374380 | 0.71 | NLRP3 (0.31) | PREP | |
| SCHEMBL27835331 | 0.69 | PREP (0.38) | MAPTALDH1A1SMN1; SMN2PREPPTGS2 | |
| SCHEMBL28367572 | 0.68 | TSHR (0.32) | ALOX15 | |
| SCHEMBL9869334 | 0.68 | TYR (0.52) | TYRMAPTALDH1A1SMN1; SMN2GAA | |
| SCHEMBL27946298 | 0.68 | KDM4E (0.34) | MAPTALDH1A1KDM4EHPGDHSD17B10 | |
| SCHEMBL10861612 | 0.67 | CYP19A1 (0.36) | MAPTALDH1A1PREPPTGS2LMNA | |
| SCHEMBL156442 | 0.64 | — | — | |
| SCHEMBL11301962 | 0.64 | TYR (0.52) | TYRMAPTALDH1A1GAA | |
| SCHEMBL4741973 | 0.63 | — | — | |
| SCHEMBL30835563 | 0.63 | KDM4E (0.33) | MAPTALDH1A1SMN1; SMN2PREPLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4134901-A | MERCAPTO SUBSTITUTED THIOPHENE-ONES | LEVER BROTHERS COMPANY (US) | 1979-01-16 | — | — | US | disclosed |