Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 7/20 | 0.62 |
| ▸ | MAPT | P10636 | 5/20 | 0.62 |
| ▸ | SLC22A6 | Q4U2R8 | 4/20 | 0.62 |
| ▸ | SLC22A8 | Q8TCC7 | 4/20 | 0.62 |
| ▸ | SLC22A11 | Q9NSA0 | 4/20 | 0.62 |
| ▸ | HPGD | P15428 | 3/20 | 0.62 |
| ▸ | NR1I2 | O75469 | 3/20 | 0.62 |
| ▸ | CTDSP1 | Q9GZU7 | 3/20 | 0.62 |
| ▸ | DNMT1 | P26358 | 1/20 | 0.62 |
| ▸ | LMNA | P02545 | 5/20 | 0.55 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.55 |
| ▸ | MEN1 | O00255 | 3/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.55 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.55 |
| ▸ | RECQL | P46063 | 1/20 | 0.55 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.55 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.52 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.52 |
| ▸ | POLB | P06746 | 2/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11518445 | 1.00 | TDP1 (0.62) | TDP1MAPTSLC22A6SLC22A8SLC22A11 | |
| Cefetrizole SCHEMBL11523034 | 0.87 | TDP1 (0.62) | TDP1MAPTSLC22A6SLC22A8SLC22A11 | |
| SCHEMBL11587846 | 0.87 | TDP1 (0.62) | TDP1MAPTSLC22A6SLC22A8SLC22A11 | |
| Cefetrizole SCHEMBL31469874 | 0.87 | TDP1 (0.62) | TDP1MAPTSLC22A6SLC22A8SLC22A11 | |
| SCHEMBL11587845 | 0.87 | TDP1 (0.62) | TDP1MAPTSLC22A6SLC22A8SLC22A11 | |
| SCHEMBL11750956 | 0.87 | LMNA (0.51) | TDP1MAPTSLC22A6SLC22A8SLC22A11 | |
| Cefetrizole SCHEMBL11523038 | 0.87 | TDP1 (0.62) | TDP1MAPTSLC22A6SLC22A8SLC22A11 | |
| Cefetrizole SCHEMBL614464 | 0.87 | TDP1 (0.62) | TDP1MAPTSLC22A6SLC22A8SLC22A11 | |
| SCHEMBL11373229 | 0.87 | CTDSP1 (0.49) | TDP1MAPTSLC22A6SLC22A8SLC22A11 | |
| Cefetrizole SCHEMBL27920203 | 0.87 | TDP1 (0.61) | TDP1MAPTSLC22A6SLC22A8SLC22A11 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4144391-A | REPLACING AN ACETOXY GROUP BY A SULFUR NUCLEOPHILE | ELI LILLY AND COMPANY (US) | 1979-03-13 | — | — | US | disclosed |