SCHEMBL11518503

SCHEMBL11518503

O=Cc1cc(CC(O)COCCO)ccc1O

nearest known ligand 0.50

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
CDK1 P06493 1/20 0.47
ERN1 O75460 9/20 0.38
NT5E P21589 1/20 0.36
ADRB2 P07550 2/20 0.36
PLA2G1B P04054 1/20 0.35
KDM6B O15054 1/20 0.34
PTPN1 P18031 1/20 0.32
POLB P06746 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11518506 0.77 CDK1 (0.51) CDK1ERN1NT5EADRB2
SCHEMBL14742604 0.71 CDK1 (0.59) CDK1ERN1NT5EPOLB
SCHEMBL5884389 0.71 CDK1 (0.73) CDK1ERN1NT5E
SCHEMBL29657596 0.70 CDK1 (0.67) CDK1ERN1NT5E
SCHEMBL5528390 0.70 CDK1 (0.67) CDK1ERN1NT5E
SCHEMBL27951129 0.70 CDK1 (0.54) CDK1
SCHEMBL27938084 0.70 CDK1 (0.54) CDK1
SCHEMBL13558573 0.70 POLB (0.35) POLB
SCHEMBL3837560 0.70 CA1 (0.47)
SCHEMBL19757236 0.69 CDK1 (0.81) CDK1ERN1NT5E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4154674-A SELECTIVE REMOVAL OF ANIONS OR CATIONS USING ION EXCHANGE RESINS YEDA RESEARCH & DEVELOPMENT CO., LTD. (IL) 1979-05-15 US disclosed