Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | FPR2 | P25090 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3837560 | 0.78 | CA1 (0.47) | MAPTALDH1A1 | |
| SCHEMBL9906222 | 0.76 | TSHR (0.50) | ALDH1A1 | |
| SCHEMBL13558574 | 0.76 | POLB (0.32) | POLB | |
| SCHEMBL1170181 | 0.76 | CA1 (0.45) | MAPTALDH1A1 | |
| SCHEMBL20958127 | 0.76 | CA1 (0.45) | MAPTALDH1A1 | |
| SCHEMBL641315 | 0.75 | ALDH1A1 (0.33) | MAPTALDH1A1HSD17B10 | |
| Adipic Acid SCHEMBL31607630 | 0.72 | LTA4H (0.46) | MAPT | |
| SCHEMBL8401423 | 0.71 | HSD17B10 (0.39) | POLBMAPTHSD17B10 | |
| SCHEMBL11518503 | 0.70 | CDK1 (0.47) | POLB | |
| SCHEMBL13185196 | 0.67 | APP (0.53) | ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120276001-A1 | BIFUNCTIONAL POLYAZAMACROCYCLIC CHELATING AGENTS | Nordion (Canada) Inc (CA) | 2012-11-01 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120276001-A1 | BIFUNCTIONAL POLYAZAMACROCYCLIC CHELATING AGENTS | LPXN, FCGRT, F13A1 | POLB 68/4885MAPT 3836/4885FPR2 604/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.