Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DHODH | Q02127 | 1/20 | 0.48 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | CA2 | P00918 | 4/20 | 0.40 |
| ▸ | CA12 | O43570 | 3/20 | 0.40 |
| ▸ | CA1 | P00915 | 3/20 | 0.40 |
| ▸ | CA9 | Q16790 | 3/20 | 0.40 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.38 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.38 |
| ▸ | PIK3CB | P42338 | 1/20 | 0.38 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.38 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11522204 | 0.89 | POLB (0.47) | CA2CA12CA1CA9MEN1 | |
| SCHEMBL11519736 | 0.87 | NPC1 (0.43) | GAANPC1CA2CA12CA1 | |
| SCHEMBL11519775 | 0.87 | BDKRB1 (0.46) | CA2CA12CA1CA9PIK3CD | |
| SCHEMBL10784109 | 0.85 | NPC1 (0.47) | GAANPC1CA2CA12CA1 | |
| SCHEMBL11521140 | 0.84 | CA12 (0.52) | NPC1CA2CA12CA1CA9 | |
| SCHEMBL11521258 | 0.84 | NPC1 (0.58) | NPC1CA2CA1CA9KDM4E | |
| SCHEMBL10784629 | 0.84 | MEN1 (0.48) | GAANPC1MEN1MAPTKMT2A | |
| SCHEMBL11524372 | 0.83 | NPC1 (0.42) | GAANPC1CA2CA12CA1 | |
| SCHEMBL11642992 | 0.83 | NPC1 (0.56) | DHODHGAANPC1CA2CA12 | |
| SCHEMBL11312537 | 0.83 | HTT (0.47) | GAACA2CA1CA9KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4176192-A | ANTHELMINTICS | HOECHST AKTIENGESELLSCHAFT (DE) | 1979-11-27 | — | — | US | disclosed |