SCHEMBL11518697

SCHEMBL11518697

CCCOC(=O)c1ccc(O)c(N)c1

nearest known ligand 0.66

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 1/20 0.66
POLB P06746 1/20 0.66
ESR1 P03372 5/20 0.60
TSHR P16473 4/20 0.60
ALDH1A1 P00352 2/20 0.60
SLC6A2 P23975 2/20 0.60
CHRM1 P11229 1/20 0.60
KDR P35968 1/20 0.60
TDP1 Q9NUW8 1/20 0.60
CYP1A2 P05177 4/20 0.54
CYP2C19 P33261 3/20 0.54
CYP2D6 P10635 3/20 0.54
CYP3A4 P08684 2/20 0.54
SCN1A P35498 2/20 0.54
KCNH2 Q12809 2/20 0.54
SCN2A Q99250 2/20 0.54
SCN3A Q9NY46 2/20 0.54
HRH3 Q9Y5N1 2/20 0.54
MAOA P21397 1/20 0.54
SIGMAR1 Q99720 1/20 0.54

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11730053 0.88 ALDH1A1 (0.67) KDM4EPOLBESR1TSHRALDH1A1
SCHEMBL2708353 0.87 CA1 (0.72) KDM4EPOLBESR1CYP1A2CYP3A4
SCHEMBL27826346 0.87 TSHR (0.59) KDM4EPOLBESR1TSHRALDH1A1
SCHEMBL31890210 0.87 CA1 (0.72) KDM4EPOLBESR1CYP1A2CYP3A4
Hydrochloric Acid SCHEMBL14128574 0.85 CA1 (0.70) KDM4EPOLBESR1CYP1A2CYP3A4
SCHEMBL3453843 0.85 CA12 (0.74) KDM4EPOLBESR1TSHRALDH1A1
SCHEMBL5386629 0.84 TDP1 (0.56) KDM4EPOLBESR1TSHRALDH1A1
SCHEMBL11395472 0.84 ALDH1A1 (0.58) KDM4EPOLBESR1TSHRALDH1A1
SCHEMBL10398250 0.83 KDM4E (0.64) KDM4EPOLBESR1TSHRALDH1A1
SCHEMBL26417380 0.82 CYP2D6 (0.59) KDM4EPOLBESR1TSHRSLC6A2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4150046-A ORGANIC PIGMENTS HOECHST AKTIENGESELLSCHAFT (DE) 1979-04-17 US disclosed